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AstraZeneca"},{"orgOrder":0,"company":"FibroGen","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Acquisition","leadProduct":"Roxadustat","moa":"Hypoxia-inducible factor prolyl hydroxylase","graph1":"Nephrology","graph2":"Approved FDF","graph3":"FibroGen","amount2":0.22,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Nephrology","amount2New":0.22,"dosageForm":"Tablet, Film Coated","sponsorNew":"FibroGen \/ AstraZeneca","highestDevelopmentStatusID":"15","companyTruncated":"FibroGen \/ AstraZeneca"},{"orgOrder":0,"company":"FibroGen","sponsor":"Fortis Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2023","type":"Licensing Agreement","leadProduct":"FOR46","moa":"Membrane cofactor protein (CD46)","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"FibroGen","amount2":0.20000000000000001,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.20000000000000001,"dosageForm":"Infusion","sponsorNew":"FibroGen \/ FibroGen","highestDevelopmentStatusID":"7","companyTruncated":"FibroGen \/ FibroGen"},{"orgOrder":0,"company":"FibroGen","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2024","type":"Inapplicable","leadProduct":"FOR46","moa":"Membrane cofactor protein (CD46)","graph1":"Oncology","graph2":"Phase I","graph3":"FibroGen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"FibroGen \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"FibroGen \/ Undisclosed"},{"orgOrder":0,"company":"FibroGen","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"FG-3246","moa":"PSMA","graph1":"Oncology","graph2":"Phase II","graph3":"FibroGen","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"FibroGen \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"FibroGen \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals by FibroGen

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : AstraZeneca acquires the China rights of certain FibroGen assets, including Ai Rui Zhuo (roxadustat), approved for the treatment of anemia in chronic kidney disease.

                          Product Name : Ai Rui Zhuo

                          Product Type : Miscellaneous

                          Upfront Cash : $135.0 million

                          September 02, 2025

                          Lead Product(s) : Roxadustat

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : AstraZeneca

                          Deal Size : $220.0 million

                          Deal Type : Acquisition

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                          02

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FG-3246 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Prostatic Neoplasms, Castration-Resistant.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          February 24, 2025

                          Lead Product(s) : FG-3246

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Through the acquisition, AstraZeneca will integrate FibroGen China and gain full rights to Evrenzo (roxadustat) in China. It is currently being evaluated for the treatment of chronic kidney disease.

                          Product Name : Evrenzo

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          February 20, 2025

                          Lead Product(s) : Roxadustat

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : AstraZeneca

                          Deal Size : $160.0 million

                          Deal Type : Acquisition

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                          04

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Pamrevlumab is a potential first-in-class anti-CTGF fully human monoclonal antibody being developed by FibroGen to inhibit the activity of CTGF, in patients with pancreatic cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          July 30, 2024

                          Lead Product(s) : Pamrevlumab,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FG-3165 is a galectin-9 (Gal9) targeted antibody, which is currently being evaluated for the treatment of patients with neoplasms & its phase study will start in 2H 2024.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 03, 2024

                          Lead Product(s) : FG-3165

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : The collaboration aims to focus on the development of FG-3165, a galectin-9 (Gal9) targeted antibody, combined with Libtayo for treating patients related to neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          June 03, 2024

                          Lead Product(s) : FG-3165,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FOR46 (FG-3246) is a potential first-in-class anti-CD46 antibody drug conjugate (ADC) with an MMAE-containing payload. It is being evaluated for metastatic castration-resistant prostate cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          April 02, 2024

                          Lead Product(s) : FOR46

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FG-3019 (pamrevlumab) is a CTGF inhibitor in phase 2/3 trials, combined with gemcitabine and nab-paclitaxel for metastatic pancreatic ductal adenocarcinoma.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 25, 2024

                          Lead Product(s) : Pamrevlumab,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FG-3019 (pamrevlumab) is a potential first-in-class antibody being developed to inhibit the activity of CTGF, a common factor in fibrotic and proliferative disorders, which is investigated for the treatment of ambulatory patients with Duchenne muscular d...

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 29, 2023

                          Lead Product(s) : Pamrevlumab,Deflazacort

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : FG-3019 (pamrevlumab) is a potential first-in-class antibody being developed to inhibit the activity of CTGF, a common factor in fibrotic and proliferative disorders, which is investigated for the treatment of Idiopathic Pulmonary Fibrosis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          June 26, 2023

                          Lead Product(s) : Pamrevlumab

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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