[{"orgOrder":0,"company":"Extend Biosciences","sponsor":"Integrated Medical Development | National Institute of Diabetes and Digestive and Kidney Diseases | Pharmaceutical Research Associates","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Other Large Molecule","year":"2022","type":"Inapplicable","leadProduct":"EXT608","moa":"PTH receptor","graph1":"Undisclosed","graph2":"Phase I","graph3":"Extend Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Injection","sponsorNew":"Extend Biosciences \/ Integrated Medical Development | National Institute of Diabetes and Digestive and Kidney Diseases | Pharmaceutical Research Associates","highestDevelopmentStatusID":"6","companyTruncated":"Extend Biosciences \/ Integrated Medical Development | National Institute of Diabetes and Digestive and Kidney Diseases | Pharmaceutical Research Associates"},{"orgOrder":0,"company":"Extend Biosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"Teriparatide","moa":"Parathyroid hormone receptor","graph1":"Endocrinology","graph2":"Phase I","graph3":"Extend Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Extend Biosciences \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Extend Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Extend Biosciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Other Large Molecule","year":"2025","type":"Inapplicable","leadProduct":"EXT608","moa":"PTH receptor","graph1":"Endocrinology","graph2":"Phase II","graph3":"Extend Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Extend Biosciences \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Extend Biosciences \/ Undisclosed"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          World Drug Safety EU
                          Not Confirmed
                          World Drug Safety EU
                          Not Confirmed

                          Details : EXT608 is a Other Large Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Hypoparathyroidism.

                          Product Name : Undisclosed

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          May 25, 2025

                          Lead Product(s) : EXT608

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          World Drug Safety EU
                          Not Confirmed
                          World Drug Safety EU
                          Not Confirmed

                          Details : EXT608 is a long-acting derivative of parathyroid hormone (PTH). Developed using ExtendBio’s D-VITylation® platform, the compound is fully active at the PTH receptor upon injection for the treatment of hypoparathyroidism.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          November 05, 2023

                          Lead Product(s) : Teriparatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          World Drug Safety EU
                          Not Confirmed
                          World Drug Safety EU
                          Not Confirmed

                          Lead Product(s) : EXT608

                          Therapeutic Area : Undisclosed

                          Study Phase : Phase I

                          Sponsor : Integrated Medical Development | National Institute of Diabetes and Digestive and Kidney Diseases | Pharmaceutical Research Associates

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          June 07, 2022

                          Lead Product(s) : EXT608

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Integrated Medical Development | National Institute of Diabetes and Digestive and Kidney Diseases | Pharmaceutical Research Associates

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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