
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Frunexian
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Cadrenal Therapeutics
Deal Size : $15.0 million
Deal Type : Acquisition
Cadrenal Acquires eXIthera’s Factor XIa Inhibitors Portfolio
Details : The Acquisition enhances the Company’s pipeline by adding novel assets, including frunexian, a first-in-class, Phase 2-ready IV Factor XIa inhibitor in acute and chronic anticoagulation settings.
Product Name : EP-7041
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 15, 2025
Lead Product(s) : Frunexian
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Cadrenal Therapeutics
Deal Size : $15.0 million
Deal Type : Acquisition

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Lead Product(s) : EP-7041
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
COVID-19 ThromboprophylaXIs Study of Novel FXIa Inhibitor Frunexian (EP-7041) in ICU Patients
Details : EP-7041 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Thrombocytopenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 10, 2021
Lead Product(s) : EP-7041
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : EP-7041
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
eXIthera Announces Publication of EP-7041 Data Demonstrating Safe Antithrombotic Activity in ECMO
Details : By preferentially inhibiting thrombosis but not normal hemostasis, EP-7041 holds the promise of preventing circuit and vascular thromboembolism with substantially less inhibition of the local hemostasis required for bleeding control in trauma or surgical...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 17, 2020
Lead Product(s) : EP-7041
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : EP-7041
Therapeutic Area : Orthopedics/Orthopedic Surgery
Study Phase : Phase I
Sponsor : IDT CMAX Clinical Trials | Syneos Health | CPR Pharma Services
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : EP-7041 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Arthroplasty, Replacement, Knee.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 26, 2016
Lead Product(s) : EP-7041
Therapeutic Area : Orthopedics/Orthopedic Surgery
Highest Development Status : Phase I
Sponsor : IDT CMAX Clinical Trials | Syneos Health | CPR Pharma Services
Deal Size : Inapplicable
Deal Type : Inapplicable
