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            Details:

            XVR012 is a cocktail of XVR013m and XVR014, targets three distinct epitopes. It is currently being evaluated in preclinical studies for the treatment of Covid-19 infection.

            Lead Product(s): XVR013m,XVR014

            Therapeutic Area: Infections and Infectious Diseases Product Name: XVR012

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 15, 2024

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            The funding will be used by ExeVir for pre-clinical research towards prophylactic and therapeutic solutions including, XVR021 for dengue by leveraging its unique, modular llama-derived antibody (VHH) technology platform to generate multi-specific antibodies.

            Lead Product(s): XVR021

            Therapeutic Area: Infections and Infectious Diseases Product Name: XVR021

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Flanders Innovation & Entrepreneurship

            Deal Size: $1.7 million Upfront Cash: Undisclosed

            Deal Type: Funding June 28, 2023

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            XVR013 targets a conserved region in the spike S2 subunit that is essential for viral entry. It neutralizes all previous and current variants of concern and the currently most frequently circulating variants, including XBB, XBB.1.5, BQ.1.1 and BF.7.

            Lead Product(s): XVR013

            Therapeutic Area: Infections and Infectious Diseases Product Name: XVR013

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: VIB

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 13, 2023

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            The EIB financing will help to advance ExeVir’s lead asset, XVR012, into clinical trials for COVID-19. XVR012, is a potent COVID-19 neutralizing antibody that targets the S1 and S2 region of the coronavirus.

            Lead Product(s): XVR012

            Therapeutic Area: Infections and Infectious Diseases Product Name: XVR012

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: European Investment Bank

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Financing January 09, 2023

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            Unique llama-derived VHH72-Fc antibody (XVR011) for potential treatment and prevention of Covid-19, ready to start first-in-human trials.

            Lead Product(s): VHH72-Fc antibody

            Therapeutic Area: Infections and Infectious Diseases Product Name: XVR011

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: VIB

            Deal Size: $50.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing March 16, 2021

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            Lead asset VHH72-Fc binds to a unique epitope that is conserved in SARS-CoV-1 and SARS-CoV-2 viruses and this binding prevents these viruses from entering the cell.

            Lead Product(s): VHH72-FC,Ad26.COV2-S

            Therapeutic Area: Infections and Infectious Diseases Product Name: VHH72-FC

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Undisclosed

            Deal Size: $27.1 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing May 28, 2020

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