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    [{"orgOrder":0,"company":"Kinnjiu Biopharma","sponsor":"Kinnate Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2023","type":"Acquisition","leadProduct":"Exarafenib","moa":"||RAF","graph1":"Oncology","graph2":"Phase I","graph3":"Kinnjiu Biopharma","amount2":0.02,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.02,"dosageForm":"Undisclosed","sponsorNew":"Kinnjiu Biopharma \/ Kinnate Biopharma","highestDevelopmentStatusID":"6","companyTruncated":"Kinnjiu Biopharma \/ Kinnate Biopharma"},{"orgOrder":0,"company":"Kinnjiu Biopharma","sponsor":"Kinnate Biopharma","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Exarafenib","moa":"||RAF","graph1":"Oncology","graph2":"Phase I","graph3":"Kinnjiu Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kinnate Biopharma \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Kinnate Biopharma \/ Undisclosed"},{"orgOrder":0,"company":"Kinnate Biopharma","sponsor":"OrbiMed Asia Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Series A Financing","leadProduct":"Exarafenib","moa":"RAF","graph1":"Oncology","graph2":"Phase I","graph3":"Kinnate Biopharma","amount2":0.040000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.040000000000000001,"dosageForm":"Undisclosed","sponsorNew":"Kinnate Biopharma \/ OrbiMed Asia Partners","highestDevelopmentStatusID":"6","companyTruncated":"Kinnate Biopharma \/ OrbiMed Asia Partners"},{"orgOrder":0,"company":"Kinnate 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I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kinnate Biopharma \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Kinnate Biopharma \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals for Exarafenib

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                            01

                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Pierre Fabre

                            Deal Size : $30.5 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Sells Investigational Pan-RAF Inhibitor Exarafenib to Pierre Fabre

                            Details : Through the agreement, Pierre Fabre will access development and global commercialization of Exarafenib, an investigational pan-RAF inhibitor evaluated for NRAS-mutated melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            March 01, 2024

                            Lead Product(s) : Exarafenib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Pierre Fabre

                            Deal Size : $30.5 million

                            Deal Type : Agreement

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                            02

                            Kinnate Biopharma

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                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : XOMA

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Kinnate Biopharma to Be Acquired By XOMA Corporation for Up to $2.5879 Per Share

                            Details : XOMA gains access to KIN-2787 (exarafenib), a potent and selective investigational small molecule pan-RAF inhibitor, being evaluated for BRAF/NRAS-mutated advanced or metastatic solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 16, 2024

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : XOMA

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            03

                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First Report of Positive Dose Escalation Data Supports Best-in-Class Profile for Investigational Exarafenib as...

                            Details : KIN-2787 (exarafenib) is an orally administered, potent and selective investigational small molecule pan-RAF inhibitor, designed to target BRAF Class II and Class III alterations, it is a potential treatment for NRAS mutation-positive melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 17, 2023

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Kinnjiu Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Kinnate Biopharma

                            Deal Size : $24.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Announces Acquisition of Ownership Stake from Series A Investors of the China Joint Ven...

                            Details : KIN-2787, is an orally available small molecule pan-RAF inhibitor being developed for the treatment of patients with lung cancer, melanoma, and other solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 21, 2023

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Kinnate Biopharma

                            Deal Size : $24.0 million

                            Deal Type : Acquisition

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                            05

                            Kinnjiu Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Kinnate Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Announces Acquisition of Ownership Stake from Series A Investors of the China Joint Ven...

                            Details : KIN-2787 (exarafenib), is an orally available small molecule pan-RAF inhibitor being developed for the treatment of patients with lung cancer, melanoma, and other solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 21, 2023

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Kinnate Biopharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Kinnate Biopharma

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                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Announces Recent Corporate Updates, Including on the Ongoing KIN-2787 Monotherapy Dose ...

                            Details : KIN-2787, a pan-RAF inhibitor, achieved meaningful exposures that were dose proportional and exceeded the predicted efficacious thresholds based on preclinical models. KIN-2787 cleared the predicted efficacious dose at 300 mg bid.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 11, 2022

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Kinnate Biopharma

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                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Receives Fast Track Designation from the U.S. Food and Drug Administration for KIN-2787...

                            Details : KIN-2787 is an orally available, potent and selective small molecule pan-RAF inhibitor being evaluated in KN-8701, an ongoing Phase 1 global clinical trial in patients with solid tumors harboring BRAF alterations or who have NRAS mutant melanoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 21, 2022

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Kinnate Biopharma

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                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Highlights Data from its Lead RAF Candidate, KIN-2787, and RAF Clinico-Genomics Landsca...

                            Details : Daily KIN-2787 treatment resulted in tumor growth inhibition in human melanoma xenograft models bearing Class I, II and III BRAF alterations as well as NRAS mutation and was associated with MAPK pathway suppression.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 08, 2022

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Kinnate Biopharma

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                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Announces Acceptance of Abstracts for Presentation at the American Association for Canc...

                            Details : In preclinical studies, KIN-2787, small molecule pan-RAF inhibitor has demonstrated its potential as a promising next-generation RAF inhibitor with unique properties that have demonstrated potent activity against a variety of oncogenic BRAF-driven cancer...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 08, 2022

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Kinnate Biopharma

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                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kinnate Biopharma Inc. Selected to Deliver Oral Presentation on its RAF Inhibitor Candidate Program at the Vir...

                            Details : KIN-2787 is a promising next-generation RAF inhibitor with demonstrated capabilities in overcoming well-characterized resistance mechanism, also has shown potent activity against a variety of oncogenic BRAF-driven lung cancers in preclinical studies.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 14, 2022

                            Lead Product(s) : Exarafenib,Binimetinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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