
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : VirTus Respiratory Research Ltd
Deal Size : Inapplicable
Deal Type : Inapplicable
ETH47 Nasal Spray Safety and Effect In Asthma After Rhinovirus Challenge
Details : ETH47 is a Oligonucleotide drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Asthma.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 11, 2025
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : VirTus Respiratory Research Ltd
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH47
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ETH47 SAD Safety, Tolerability, PK & PD In Healthy Adults
Details : ETH47 is a Oligonucleotide drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 08, 2025
Lead Product(s) : ETH47
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : EU4Health
Deal Size : $11.3 million
Deal Type : Funding
Ethris Gets €10M EU4Health Grant to Advance ETH47 mRNA Antiviral Program
Details : The funding will support NoVir, a comprehensive project including several preclinical and clinical studies to evaluate the potential of ETH47, Ethris’ lead, first-in-class mRNA-based therapy.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
May 06, 2025
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : EU4Health
Deal Size : $11.3 million
Deal Type : Funding

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Lead Product(s) : ETH52
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery
Recipient : Lonza Group
Deal Size : Undisclosed
Deal Type : Collaboration
Ethris And Lonza Team Up For Spray-Dried mRNA Respiratory Vaccines
Details : The initial focus of the collaboration is to develop a first-in-class mRNA vaccine candidate against influenza delivered nasally.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
April 07, 2025
Lead Product(s) : ETH52
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery
Recipient : Lonza Group
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ETH47 Phase 1 Data Shows Promise for Uncontrolled Asthma Treatment
Details : ETH47 is a lead mRNA candidate encoding interferon lambda (IFNλ). It is being evaluated in the early-stage clinical trial studies for the treatment of asthma.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
January 30, 2025
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Ethris Announces Positive Initial Phase 1 Data for ETH47 mRNA Nasal Delivery
Details : ETH47 is a lead mRNA candidate encoding interferon lambda (IFNλ). It is being evaluated in the early-stage clinical trial studies for the treatment of asthma.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
June 25, 2024
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Bill & Melinda Gates Foundation
Deal Size : $5.0 million
Deal Type : Funding
Ethris Announces $5 Million in Funding to Prepare Lead Candidate ETH47 for Phase 2 Study
Details : The funding aims to support the company first-in-class mRNA-based product candidate ETH47, which is being evaluated in the early-stage clinical trial studies for the treatment of asthma.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
June 18, 2024
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Bill & Melinda Gates Foundation
Deal Size : $5.0 million
Deal Type : Funding

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Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ETH47 is a first-in-class, broadly protective antiviral candidate which is under phase 1 clinical development for the treatment and prophylaxis of viral asthma exacerbations.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 18, 2023
Lead Product(s) : ETH47
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH47
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MHRA approved company to proceed with a Phase 1 clinical trial for its inhaled mRNA program, ETH47 (induce a mucosal innate immune defense), in healthy participants for the treatment and prophylaxis of respiratory viral infections.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
November 28, 2023
Lead Product(s) : ETH47
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ETH51
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Heqet Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the agreement, Heqet will lead the development of ETH51, RNA-based therapeutics for heart attack and heart failure, while Ethris will provide its proprietary Stabilized NanoParticle (SNaP) LNP platform to deliver ncRNA payloads to the ...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 13, 2023
Lead Product(s) : ETH51
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Heqet Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
