[{"orgOrder":0,"company":"Epsilogen","sponsor":"Innovate Biopharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2020","type":"Funding","leadProduct":"EPS 201","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epsilogen \/ Innovate Biopharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Epsilogen \/ Innovate Biopharmaceuticals"},{"orgOrder":0,"company":"Epsilogen","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"Mov18 IgE","moa":"Folate-alpha receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epsilogen \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epsilogen \/ Inapplicable"},{"orgOrder":0,"company":"Epsilogen","sponsor":"British Patient Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2024","type":"Series B Financing","leadProduct":"Mov18 IgE","moa":"Folate-alpha receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Epsilogen \/ British Patient Capital","highestDevelopmentStatusID":"6","companyTruncated":"Epsilogen \/ British Patient Capital"},{"orgOrder":0,"company":"Epsilogen","sponsor":"Novartis Venture Fund","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2022","type":"Series B Financing","leadProduct":"Mov18 IgE","moa":"Folate-alpha receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Epsilogen \/ Novartis Venture Fund","highestDevelopmentStatusID":"6","companyTruncated":"Epsilogen \/ Novartis Venture Fund"},{"orgOrder":0,"company":"Epsilogen","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Mov18 IgE","moa":"Folate-alpha receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Epsilogen \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epsilogen \/ Inapplicable"},{"orgOrder":0,"company":"Epsilogen","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Mov18 IgE","moa":"Folate-alpha receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Epsilogen \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Epsilogen \/ Inapplicable"},{"orgOrder":0,"company":"Epsilogen","sponsor":"TigaTx","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Acquisition","leadProduct":"EPS 401","moa":"EGFR","graph1":"Oncology","graph2":"IND Enabling","graph3":"Epsilogen","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Epsilogen \/ Epsilogen","highestDevelopmentStatusID":"5","companyTruncated":"Epsilogen \/ Epsilogen"}]

Find Clinical Drug Pipeline Developments & Deals by Epsilogen

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The acquisition bolsters Epsilogen’s pipeline by adding EPS 401 (formerly TIGA-001), an anti-EGFR IgA antibody. It is being evaluated for treating neoplasms.

                          Product Name : EPS 401

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          April 07, 2025

                          Lead Product(s) : EPS 401

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Recipient : TigaTx

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : MOv18 IgE, is the first therapeutic IV infused IgE antibody which is being investigated in patients with platinum-resistant ovarian cancer (PROC).

                          Product Name : MOv18 IgE

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          December 02, 2024

                          Lead Product(s) : Mov18 IgE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The financing aims to fund the clinical development of company-lead product MOv18 IgE is the first therapeutic IgE antibody targets FRα. It is being evaluated for the treatment of ovarian cancer.

                          Product Name : Mov18 IgE

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          September 09, 2024

                          Lead Product(s) : Mov18 IgE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : British Patient Capital

                          Deal Size : $47.9 million

                          Deal Type : Series B Financing

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                          04

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : MOv18 IgE, is the first therapeutic IV infused IgE antibody which is being investigated in patients with platinum-resistant ovarian cancer (PROC).

                          Product Name : Mov18 IgE

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          August 07, 2024

                          Lead Product(s) : Mov18 IgE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : The proceeds from the financing will enable Epsilogen to establish clinical proof of concept for lead drug candidate MOv18 IgE in a phase Ib trial in platinum-resistant ovarian cancer, an aggressive cancer with poor treatment alternatives.

                          Product Name : MOv18 IgE

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          February 03, 2022

                          Lead Product(s) : Mov18 IgE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Novartis Venture Fund

                          Deal Size : $41.2 million

                          Deal Type : Series B Financing

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                          06

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Epsilogen will collaborate with King’s College London (KCL) and use the funding from the grant to further develop the company’s novel cancer immunotherapeutic EPS 201.

                          Product Name : EPS 201

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          October 21, 2020

                          Lead Product(s) : EPS 201

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Innovate Biopharmaceuticals

                          Deal Size : $1.3 million

                          Deal Type : Funding

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                          07

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : MOv18 IgE, at the doses administered, was found to be well tolerated in almost all patients, with urticaria1 being the most frequently observed adverse event.

                          Product Name : Mov18 IgE

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 27, 2020

                          Lead Product(s) : Mov18 IgE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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