Lead Product(s) : Entinostat,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Experimental Drug that Boosts Immunotherapy Shows Promise in Bladder Cancer Study
Details : When treated with entinostat in combination with immunotherapy, two-thirds of mice had a complete disappearance of their tumors and none of the mice had relapse of their tumors when taken off the treatment.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 16, 2021
Lead Product(s) : Entinostat,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat,Exemestane
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Citigroup
Deal Size : $115.0 million
Deal Type : Public Offering
Details : The Company's lead product candidate, entinostat, a class I HDAC inhibitor, is being tested in a Phase 3 combination trial with exemestane for treatment of advanced HR+, HER2- breast cancer and has been evaluated in combination with several approved PD-1...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 05, 2020
Lead Product(s) : Entinostat,Exemestane
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Citigroup
Deal Size : $115.0 million
Deal Type : Public Offering
Lead Product(s) : Entinostat,Exemestane
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Syndax Pharmaceuticals Highlights 2020 Clinical and Corporate Outlook
Details : Syndax Pharmaceuticals is on track to file for regulatory approval in 2020 and to become a fully-integrated oncology company with the launch of entinostat in HR+ breast cancer expected in 2021.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 01, 2020
Lead Product(s) : Entinostat,Exemestane
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat,Exemestane,Goserelin Acetate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The trial did not achieve the primary endpoint of demonstrating a statistically significant overall survival (OS) benefit over hormone therapy alone.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 21, 2020
Lead Product(s) : Entinostat,Exemestane,Goserelin Acetate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : AstraZeneca | Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 23, 2019
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : AstraZeneca | Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
An Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2018
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 30, 2018
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Syndax Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Entinostat With Nivolumab Plus Ipilimumab in Previously Treated Renal Cell Carcinoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 11, 2018
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 29, 2018
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Indiana University Melvin and Bren Simon Cancer Center | Syndax Pharmaceuticals | Clinigen Group
Deal Size : Inapplicable
Deal Type : Inapplicable
High Dose IL 2 and Entinostat in RCC
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 18, 2018
Lead Product(s) : Entinostat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Indiana University Melvin and Bren Simon Cancer Center | Syndax Pharmaceuticals | Clinigen Group
Deal Size : Inapplicable
Deal Type : Inapplicable