[{"orgOrder":0,"company":"Eoc Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase III","graph3":"Eoc Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Eoc Pharma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Eoc Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Kyowa Kirin","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"Kyowa Kirin","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kyowa Kirin \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Kyowa Kirin \/ Undisclosed"},{"orgOrder":0,"company":"Eoc Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase III","graph3":"Eoc Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Eoc Pharma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Eoc Pharma \/ Undisclosed"},{"orgOrder":0,"company":"University of Maryland, Baltimore","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"University of Maryland, Baltimore","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Maryland, Baltimore \/ Syndax Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"University of Maryland, Baltimore \/ Syndax Pharmaceuticals"},{"orgOrder":0,"company":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins","sponsor":"Syndax Pharmaceuticals | Bristol Myers Squibb | National Cancer Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins \/ Syndax Pharmaceuticals | Bristol Myers Squibb | National Cancer Institute","highestDevelopmentStatusID":"8","companyTruncated":"Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins \/ Syndax Pharmaceuticals | Bristol Myers Squibb | National Cancer Institute"},{"orgOrder":0,"company":"UNC Lineberger Comprehensive Cancer Center","sponsor":"Syndax Pharmaceuticals | National Cancer Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase I","graph3":"UNC Lineberger Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"UNC Lineberger Comprehensive Cancer Center \/ Syndax Pharmaceuticals | National Cancer Institute","highestDevelopmentStatusID":"6","companyTruncated":"UNC Lineberger Comprehensive Cancer Center \/ Syndax Pharmaceuticals | National Cancer Institute"},{"orgOrder":0,"company":"UNC Lineberger Comprehensive Cancer Center","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"UNC Lineberger Comprehensive Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"UNC Lineberger Comprehensive Cancer Center \/ Syndax Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"UNC Lineberger Comprehensive Cancer Center \/ Syndax Pharmaceuticals"},{"orgOrder":0,"company":"Abramson Cancer Center at Penn Medicine","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase I","graph3":"Abramson Cancer Center at Penn Medicine","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Abramson Cancer Center at Penn Medicine \/ Syndax Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Abramson Cancer Center at Penn Medicine \/ Syndax Pharmaceuticals"},{"orgOrder":0,"company":"Vanderbilt-Ingram Cancer Center","sponsor":"AstraZeneca | Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase I","graph3":"Vanderbilt-Ingram Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Vanderbilt-Ingram Cancer Center \/ AstraZeneca | Syndax Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Vanderbilt-Ingram Cancer Center \/ AstraZeneca | Syndax Pharmaceuticals"},{"orgOrder":0,"company":"University of Virginia","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase I","graph3":"University of Virginia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Virginia \/ Syndax Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"University of Virginia \/ Syndax Pharmaceuticals"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Syndax Pharmaceuticals \/ Merck & Co","highestDevelopmentStatusID":"7","companyTruncated":"Syndax Pharmaceuticals \/ Merck & Co"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"F. 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Undisclosed"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Undisclosed","graph2":"Phase I","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Syndax Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Syndax Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Undisclosed","graph2":"Phase I","graph3":"Syndax 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Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Entinostat","moa":"||Histone deacetylase","graph1":"Oncology","graph2":"Phase III","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Syndax Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Syndax Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"University of North Carolina","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Entinostat","moa":"||Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"University of North Carolina","amount2":0,"highestDevelopmentShortName":"Ph 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University School of Medicine"},{"orgOrder":0,"company":"Syndax Pharmaceuticals","sponsor":"Roberto Pili","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Entinostat","moa":"Histone deacetylase","graph1":"Oncology","graph2":"Phase II","graph3":"Syndax Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Syndax Pharmaceuticals \/ Roberto Pili","highestDevelopmentStatusID":"8","companyTruncated":"Syndax Pharmaceuticals \/ Roberto Pili"}]

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                          01

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : When treated with entinostat in combination with immunotherapy, two-thirds of mice had a complete disappearance of their tumors and none of the mice had relapse of their tumors when taken off the treatment.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 16, 2021

                          Lead Product(s) : Entinostat,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The trial did not achieve the primary endpoint of demonstrating a statistically significant overall survival (OS) benefit over hormone therapy alone.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 21, 2020

                          Lead Product(s) : Entinostat,Exemestane,Goserelin Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The Company's lead product candidate, entinostat, a class I HDAC inhibitor, is being tested in a Phase 3 combination trial with exemestane for treatment of advanced HR+, HER2- breast cancer and has been evaluated in combination with several approved PD-1...

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 12, 2020

                          Lead Product(s) : Entinostat,Exemestane

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Citigroup

                          Deal Size : $115.0 million

                          Deal Type : Public Offering

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                          04

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Syndax Pharmaceuticals is on track to file for regulatory approval in 2020 and to become a fully-integrated oncology company with the launch of entinostat in HR+ breast cancer expected in 2021.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 10, 2020

                          Lead Product(s) : Entinostat,Exemestane

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Vanderbilt-Ingram Cancer Center

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Vanderbilt-Ingram Cancer Center

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Fallopian Tube Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 23, 2019

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : AstraZeneca | Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          UNC Lineberger Comprehensive Cancer Center

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          UNC Lineberger Comprehensive Cancer Center

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Melanoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 05, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Abramson Cancer Center at Penn Medicine

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Abramson Cancer Center at Penn Medicine

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Pancreatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 30, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Roberto Pili

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Roberto Pili

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Renal Cell.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 11, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Breast Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 29, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Entinostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Renal Cell.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 18, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Roberto Pili

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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