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Find Clinical Drug Pipeline Developments & Deals for Entinostat

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                          01

                          Process Development
                          Not Confirmed
                          Process Development
                          Not Confirmed

                          Details : When treated with entinostat in combination with immunotherapy, two-thirds of mice had a complete disappearance of their tumors and none of the mice had relapse of their tumors when taken off the treatment.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 16, 2021

                          Lead Product(s) : Entinostat,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : The Company's lead product candidate, entinostat, a class I HDAC inhibitor, is being tested in a Phase 3 combination trial with exemestane for treatment of advanced HR+, HER2- breast cancer and has been evaluated in combination with several approved PD-1...

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 05, 2020

                          Lead Product(s) : Entinostat,Exemestane

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Citigroup

                          Deal Size : $115.0 million

                          Deal Type : Public Offering

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                          03

                          Process Development
                          Not Confirmed
                          Process Development
                          Not Confirmed

                          Details : Syndax Pharmaceuticals is on track to file for regulatory approval in 2020 and to become a fully-integrated oncology company with the launch of entinostat in HR+ breast cancer expected in 2021.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 01, 2020

                          Lead Product(s) : Entinostat,Exemestane

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Process Development
                          Not Confirmed
                          Process Development
                          Not Confirmed

                          Details : The trial did not achieve the primary endpoint of demonstrating a statistically significant overall survival (OS) benefit over hormone therapy alone.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 21, 2020

                          Lead Product(s) : Entinostat,Exemestane,Goserelin Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Vanderbilt-Ingram Cancer Center

                          Country arrow
                          Process Development
                          Not Confirmed

                          Vanderbilt-Ingram Cancer Center

                          Country arrow
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 23, 2019

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : AstraZeneca | Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          UNC Lineberger Comprehensive Cancer Center

                          Country arrow
                          Process Development
                          Not Confirmed

                          UNC Lineberger Comprehensive Cancer Center

                          Country arrow
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 05, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Abramson Cancer Center at Penn Medicine

                          Country arrow
                          Process Development
                          Not Confirmed

                          Abramson Cancer Center at Penn Medicine

                          Country arrow
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 30, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Roberto Pili

                          Country arrow
                          Process Development
                          Not Confirmed

                          Roberto Pili

                          Country arrow
                          Process Development
                          Not Confirmed

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 11, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bristol Myers Squibb | Syndax Pharmaceuticals | Indiana University School of Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Process Development
                          Not Confirmed
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 29, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Roberto Pili

                          Country arrow
                          Process Development
                          Not Confirmed

                          Roberto Pili

                          Country arrow
                          Process Development
                          Not Confirmed

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Indiana University Melvin and Bren Simon Cancer Center | Syndax Pharmaceuticals | Clinigen Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 18, 2018

                          Lead Product(s) : Entinostat

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Indiana University Melvin and Bren Simon Cancer Center | Syndax Pharmaceuticals | Clinigen Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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