Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Enterprise Therapeutics Granted Rare Pediatric Disease Status for ETD001 in US
Details : ETD001, is a first-in-class potential, targets the epithelial sodium channel. It is being evaluated in mid-stage clinical trial studies for the treatment of Cystic Fibrosis.
Product Name : ETD001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 26, 2024
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Enterprise Therapeutics Doses First Person with Cystic Fibrosis in Phase 2 Trial of ETD001
Details : ETD001, is a first-in-class potential, targets the epithelial sodium channel. It is being evaluated in mid-stage clinical trial studies for the treatment of Cystic Fibrosis.
Product Name : ETD001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 23, 2024
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Panakes Partners
Deal Size : $33.1 million
Deal Type : Series B Financing
Enterprise Therapeutics Closes £26 million ($33.1 million) Series B Follow-on Financing
Details : The financing will fund the Phase 2a clinical trial of the Company’s lead programme, ETD001, a novel first in class ENaC blocker, to deliver clinical proof of concept to treat cystic fibrosis.
Product Name : ETD001
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 30, 2024
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Panakes Partners
Deal Size : $33.1 million
Deal Type : Series B Financing
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : By increasing the amount of airway fluid available to hydrate mucus, ETD001 addresses the underlying mechanisms of mucus congestion, and is expected to restore lung function, reduce the frequency of lung infections and improve patient quality of life.
Product Name : ETD001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 14, 2021
Lead Product(s) : ETD001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ETD002
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ETD002. The first-in-man safety study is being conducted in healthy participants with ETD002, a TMEM16A potentiator aimed at treating all people with cystic fibrosis (CF).
Product Name : ETD002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 17, 2020
Lead Product(s) : ETD002
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ETX001
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Paper demonstrates first in class TMEM16A chloride channel potentiators, to accelerate mucociliary clearance.
Product Name : ETX001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 01, 2020
Lead Product(s) : ETX001
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ETD002
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Enterprise Therapeutics' TMEM16A portfolio includes ETD002, first of its compounds to hit clinical stage. In pre-clinical models the compound has been found to enhances the activity of TMEM16A.
Product Name : ETD002
Product Type : Other Small Molecule
Upfront Cash : $96.8 milion
July 10, 2020
Lead Product(s) : ETD002
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Acquisition
Reset All
