
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Human Donor Islet Cell,Tegoprubart
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Recipient : Sernova
Deal Size : Undisclosed
Deal Type : Agreement
Sernova Collaboration with Eledon to Advance a Cure for Type 1 Diabetes
Details : Under the agreement, Eledon will supply tegoprubart to be used as Immunosuppressive Agent in Sernova’s Phase 1/2 Cell Pouch Bio-hybrid Organ Clinical Trial in Patients with Type 1 Diabetes.
Product Name : Sernova Cell Pouch
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
July 09, 2025
Lead Product(s) : Human Donor Islet Cell,Tegoprubart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Recipient : Sernova
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Rituximab
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Tatsuo Kawai, MD, PhD
Deal Size : Inapplicable
Deal Type : Inapplicable
Tolerance Through Mixed Chimerism (Sip-Tego)
Details : Rituximab is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Renal Insufficiency.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 14, 2025
Lead Product(s) : Rituximab
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Tatsuo Kawai, MD, PhD
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : BVF Partners
Deal Size : $85.0 million
Deal Type : Public Offering
Eledon Pharmaceuticals Prices $85M Stock And Warrants Offering
Details : The proceeds from the offering will be used to advance its pipeline, which includes AT-1501 (tegoprubart), an experimental humanized monoclonal antibody, being evaluated for treating Organ Rejection.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : BVF Partners
Deal Size : $85.0 million
Deal Type : Public Offering

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Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Reports Positive Tegoprubart Data in Islet Transplantation for Type 1 Diabetes
Details : The Company’s lead product is AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Completes Enrollment in Ph 2 Trial for Tegoprubart in Kidney Transplant Patients
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 04, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Provides Enrollment Update for Phase 2 Trial of Tegoprubart for Organ Rejection
Details : AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 ligand, being developed for the prevention of rejection in kidney transplantation.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Announces Clinical Progress with Tegoprubart to Prevent Transplant Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 07, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement
Eledon Pharmaceuticals Announces Oversubscribed $50 Million Private Placement
Details : The company aims to develop AT-1501 (tegoprubart), a humanized monoclonal antibody targeting CD40L, for kidney transplantation.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
May 07, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Enrolls 12th Participant in Phase 2 BESTOW Trial for Organ Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 25, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AT-1501
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients
Details : AT-1501 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Graft Rejection.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 13, 2023
Lead Product(s) : AT-1501
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
