Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Reports Positive Tegoprubart Data in Islet Transplantation for Type 1 Diabetes
Details : The Company’s lead product is AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : BVF Partners
Deal Size : $85.0 million
Deal Type : Public Offering
Eledon Pharmaceuticals Prices $85M Stock And Warrants Offering
Details : The proceeds from the offering will be used to advance its pipeline, which includes AT-1501 (tegoprubart), an experimental humanized monoclonal antibody, being evaluated for treating Organ Rejection.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Undisclosed
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : BVF Partners
Deal Size : $85.0 million
Deal Type : Public Offering
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Provides Enrollment Update for Phase 2 Trial of Tegoprubart for Organ Rejection
Details : AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 ligand, being developed for the prevention of rejection in kidney transplantation.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
July 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Announces Clinical Progress with Tegoprubart to Prevent Transplant Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
July 05, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement
Eledon Pharmaceuticals Announces Oversubscribed $50 Million Private Placement
Details : The company aims to develop AT-1501 (tegoprubart), a humanized monoclonal antibody targeting CD40L, for kidney transplantation.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Undisclosed
July 05, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Completes Enrollment in Ph 2 Trial for Tegoprubart in Kidney Transplant Patients
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
April 09, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Enrolls 12th Participant in Phase 2 BESTOW Trial for Organ Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
March 25, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AT-1501 (tegoprubart) is an investigational, humanized IgG1 anti-CD40L antibody with high affinity for the CD40 ligand, which is investigated for the treatment of prevention of rejection in kidney transplantation.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
May 09, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The Company intends to use the net proceeds to fund the clinical development of its lead asset AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for CD40 Ligand.
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : $35.0 million
January 05, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eledon Pharmaceuticals Announces Upcoming Presentations at ASN’s Kidney Week 2022 and NEALS
Details : Tegoprubart (AT-1501) is a humanized IgG1 anti-CD40L antibody with high affinity for CD40L (also called CD154), a well-validated biological target with broad therapeutic potential. It was built around safety and engineered to maximize efficacy and half l...
Product Name : AT-1501
Product Type : Antibody
Upfront Cash : Inapplicable
October 24, 2022
Lead Product(s) : Tegoprubart
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable