Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Yosemite Capital
Deal Size : $64.0 million
Deal Type : Private Placement
Lomond Therapeutics Completes Second and Third Closings and Adds Two New Investors
Details : The net proceeds from the placement will used to fund the clincial development of ZE46-0134 (lomonitinib), which is being evaluated for the treatment of AML.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 28, 2025
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Yosemite Capital
Deal Size : $64.0 million
Deal Type : Private Placement
Lead Product(s) : ZE50-0134
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 22, 2025
Lead Product(s) : ZE50-0134
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ZE63-0302
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 17, 2025
Lead Product(s) : ZE63-0302
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Expert Systems
Deal Size : Inapplicable
Deal Type : Inapplicable
Expert Systems Celebrates Milestone in Clinical Development of Lonitoclax BCL-2 Inhibitor
Details : Lonitoclax has a best-in-class potency and selectivity against BCL-2. Currently, it is being evaluated for the treatment of chronic lymphocytic leukemia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 17, 2024
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Expert Systems
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Expert Systems
Deal Size : Undisclosed
Deal Type : Partnership
Expert Systems Expands Partnership with Eilean Therapeutics for PTPN2 Inhibitor Program
Details : The partnership aims to support the clinical advancement of Eilean's lead PTPN2 inhibitor, which is being evaluated in the preclinical trial studies for the treatment of patients related to neoplasms.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 03, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Expert Systems
Deal Size : Undisclosed
Deal Type : Partnership
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
November 27, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Deerfield Management Company
Deal Size : $44.0 million
Deal Type : Private Placement
Lomond Therapeutics Completes Reverse Merger and Closes $44 Million Private Placement
Details : The net proceeds from the placement will used to fund the clincial development of ZE46-0134 (lomonitinib), which is being evaluated for the treatment of AML.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 04, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Deerfield Management Company
Deal Size : $44.0 million
Deal Type : Private Placement
Lead Product(s) : Balamenib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eilean Approved to Initiate Trial with Balamenib, a Best-in-Class Menin Inhibitor
Details : ZE63-0302 (balamenib) is a selective best-in-class oral small molecule inhibitor of the menin-KMT2A interaction. It is being evaluated for the treatment of hematological malignancies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2024
Lead Product(s) : Balamenib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lomond’s Lonitoclax IND Cleared by FDA for Chronic Lymphocytic Leukemia
Details : Lonitoclax has a best-in-class potency and selectivity against BCL-2. Currently, it is being evaluated for the treatment of chronic lymphocytic leukemia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 15, 2024
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 03, 2024