

Lead Product(s) : Eganelisib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML
Details : Eganelisib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leukemia, Myeloid, Acute.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 01, 2024
Lead Product(s) : Eganelisib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : MEI Pharma
Deal Size : Undisclosed
Deal Type : Termination
Infinity Pharmaceuticals Announces Termination of Merger Agreement with MEI Pharma
Details : Under the termination, Infinity has continued to prepare for the initiation of a planned global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
July 24, 2023
Lead Product(s) : Eganelisib,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : MEI Pharma
Deal Size : Undisclosed
Deal Type : Termination

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Lead Product(s) : Eganelisib,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : MEI Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IPI-549 (eganelisib) is a first-in-class, oral, once-daily, immuno-oncology candidate that selectively inhibits phosphoinositide-3-kinase gamma, which is investigated in Combination with Pembrolizumab in Patients with Squamous Cell Cancer of the Head and...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 10, 2023
Lead Product(s) : Eganelisib,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : MEI Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : MEI Pharma
Deal Size : Undisclosed
Deal Type : Merger
Details : The Combination will create a company with a diverse product development pipeline led by a planned new global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma (HNSCC)
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 23, 2023
Lead Product(s) : Eganelisib,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : MEI Pharma
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IPI-54 (Eganelisb) in combination therapy has demonstrated positive resutls total tumor volume reduction is 92.8% and 85.2%, and disease control rates is 92.8% and 81.4%, in PD-L1 frontline TNBC patients.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 05, 2022
Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IPI-549 (eganelisib ), a first-in-class, oral, immuno-oncology macrophage reprogramming therapeutic addresses a fundamental biologic mechanism of immune suppression in cancer in multiple clinical studies.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 10, 2021
Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IPI-549 (eganelisib) immuno-oncology macrophage reprogramming therapeutic that selectively inhibits phosphoinositide-3-kinase gamma used as a frontline regimentriple negative breast cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 06, 2021
Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Infinity Pharmaceuticals Presents Updated Data from Phase 2 MARIO-275 Trial
Details : At the one-year landmark, 59% of patients in the ITT population receiving the eganelisib plus nivolumab combination remained alive, compared to 32% in the nivolumab control arm.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 27, 2021
Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Infinity Pharmaceuticals Hosting Webinar on MARIO-3 and MARIO-275 Phase 2 Trials
Details : MARIO-3 is a Phase 2 triplet combination study evaluating the addition of eganelisib to the approved standard of care combination of Tecentriq® and Abraxane® in the front-line setting in TNBC.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 20, 2021
Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Eganelisib,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Arcus Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Infinity to Present at The Keystone Symposia Precision Oncology Meeting
Details : In collaboration with Arcus Biosciences, Infinity is evaluating a checkpoint inhibitor-free, novel combination regimen of eganelisib plus etrumadenant (AB928, a dual adenosine receptor antagonist) plus Doxil® in advanced TNBC patients.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 14, 2021
Lead Product(s) : Eganelisib,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Arcus Biosciences
Deal Size : Inapplicable
Deal Type : Inapplicable
