
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ECC4703 is a small molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 17, 2025
Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AZD5004
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AZD5004 in Chinese Overweight/Obese Participants with or Without Type 2 Diabetes
Details : AZD5004 is a drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 25, 2025
Lead Product(s) : AZD5004
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Eccogene Earns $60M Milestone from AstraZeneca for Obesity, Diabetes Drug
Details : AstraZeneca has licensed global rights to ECC5004/AZD5004 from Eccogene. ECC5004 is currently undergoing mid-stage clinical trials for the treatment of obesity and Type 2 diabetes.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $185.0 million
October 23, 2024
Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants
Details : ECC5004 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 2.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 05, 2024
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ECC5004 RBA FE Study in Healthy Participants
Details : ECC5004 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 2.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 20, 2024
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Details : AstraZeneca will receive an exclusive license to develop and commercialize ECC5004, a small molecule GLP-1 receptor agonist, for the potential treatment of obesity, type-2 diabetes and other comorbidities, in all territories except China.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $185.0 million
November 09, 2023
Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Neutron Therapeutics
Deal Size : $25.1 million
Deal Type : Series B Financing
Details : The proceeds will support the development of Eccogene’s clinical-stage programs including Phase I trial of ECC5004, a small molecule GLP-1 receptor agonist for obesity and type 2 diabetes, and the Phase I trial of ECC4703, a THRb full agonist for NASH ...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 12, 2023
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Neutron Therapeutics
Deal Size : $25.1 million
Deal Type : Series B Financing

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Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FTIH of ECC5004 in Healthy and Diabetic Participants
Details : ECC5004 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 2.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 16, 2022
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FTIH of ECC4703 in Healthy Volunteers
Details : ECC4703 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 23, 2022
Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Eccogene Announces US IND Approval for THRβ Agonist ECC4703
Details : ECC4703 was discovered from Eccogene's internal drug discovery platform. It is a β-selective, liver targeting THR full agonist. ECC4703 has demonstrated superiority in pre-clinical studies over partial agonist MGL-3196.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 01, 2022
Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
