
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Danvatirsen,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Flamingo Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined oncology company will advance Flamingo's lead programs, Danvatirsen (antisence oligonucleotide) in a Phase II trial PEMDA-HN in Head & Neck cancer (danvatirsen in combination with pembrolizumab) and other indications; and FTX-001 targeting M...
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
March 02, 2023
Lead Product(s) : Danvatirsen,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Flamingo Therapeutics
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Fast Track Designation recieved for DYN101,an investigational antisense product candidate designed to reduce the expression of dynamin 2 protein for the treatment of Myotubular and Centronuclear Myopathies.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Nippon Shinyaku
Deal Size : Undisclosed
Deal Type : Agreement
Dynacure Announces Strategic Collaboration and Option Agreement with Nippon Shinyaku
Details : Under the terms of the agreement, Nippon Shinyaku has secured opt-in rights to exclusively pursue the development and commercialization of DYN101 in Japan depending on analysis of interim data from the Phase 1/2 study, UNITE-CNM.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
November 10, 2021
Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Nippon Shinyaku
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : DYN-101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DYN-101 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Myopathies, Structural, Congenital.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
February 08, 2021
Lead Product(s) : DYN-101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : U.S. Food and Drug Administration (FDA) has granted rare pediatric disease designation for DYN101, an investigational antisense medicine designed to modulate the expression of dynamin 2 (DNM2), for the treatment of Myotubular and Centronuclear Myopathies...
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 30, 2020
Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $54.6 million
Deal Type : Series C Financing
Dynacure Announces €50M ($55M) Series C Financing
Details : Funding supports ongoing Phase 1 / 2 'Unite-CNM' study of DYN101 in Patients with Myotubular and Centronuclear Myopathies.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
April 02, 2020
Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $54.6 million
Deal Type : Series C Financing

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Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Dynacure Announces First Patient Dosed in Phase 1 / 2 'UNITE-CNM' Study of DYN101
Details : This clinical trial, based on Ionis' technology platform, is the first investigational study testing an antisense medicine to treat Centronuclear Myopathies.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 05, 2020
Lead Product(s) : DYN101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DYN-101
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DYN-101 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Myopathies, Structural, Congenital.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
July 25, 2019
Lead Product(s) : DYN-101
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
