
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors
Details : DB-1317 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 26, 2025

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
Details : DB-1311 is a Other Large Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 01, 2025

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Lead Product(s) : DB-1418
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Avenzo Therapeutics
Deal Size : $1,200.0 million
Deal Type : Licensing Agreement
Avenzo, DualityBio Sign License for EGFR/HER3 Antibody-Drug Conjugate
Details : Under the licensing agreement, Venzo will develop, manufacture and commercialize AVZO-1418 (DB-1418), a potential best-in-class bispecific ADC for treating neoplasms.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : $50.0 million
January 07, 2025
Lead Product(s) : DB-1418
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Avenzo Therapeutics
Deal Size : $1,200.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : DB-1312,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : BeOne Medicines
Deal Size : $1,300.0 million
Deal Type : Licensing Agreement
Nona Biosciences Updates on DualityBio's ADC Collaboration with BeiGene
Details : BeiGene has exercised its exclusive option to acquire global development, manufacturing, and commercialization rights for an ADC, BG-C9074 (DB-1312) from DualityBio.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 03, 2025
Lead Product(s) : DB-1312,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : BeOne Medicines
Deal Size : $1,300.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : DB-1312
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : BeOne Medicines
Deal Size : $1,300.0 million
Deal Type : Agreement
Duality Biologics Announces B7H4 ADC Milestone Achievement and License Exercise by BeiGene
Details : Under the agreement, BeiGene will acquire an exclusive option for a global clinical and commercial license to DB-1312, an investigational antibody-drug conjugate therapy for solid tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 30, 2024
Lead Product(s) : DB-1312
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : BeOne Medicines
Deal Size : $1,300.0 million
Deal Type : Agreement

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Lead Product(s) : DB-1324
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : GSK
Deal Size : Undisclosed
Deal Type : Agreement
GSK Turns Back to China in Another Potential $1B+ ADC Deal
Details : GSK gains an exclusive option to obtain a license to develop and commercialize a potentially best-in-class ADC candidate, DB-1324 worldwide (excluding mainland China, Hong Kong, and Macau).
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : $30.0 million
December 04, 2024
Lead Product(s) : DB-1324
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : GSK
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Adcendo
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Duality Biologics Expands Adcendo Collaboration via Strategic License Agreement
Details : Adcendo exercises its option to utilize Duality's platform to further enhance its first-in-class ADC pipeline and develop highly differentiated novel ADCs for the treatment of hard-to-treat cancers.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 25, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Adcendo
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : DB-2304
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Study of DB-2304 in Healthy Adults and SLE Participants
Details : DB-2304 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lupus Erythematosus, Systemic.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
October 03, 2024
Lead Product(s) : DB-2304
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DB-1419
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors
Details : DB-1419 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
August 15, 2024
Lead Product(s) : DB-1419
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DB-1311
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : BioNTech
Deal Size : Inapplicable
Deal Type : Inapplicable
BioNTech and DualityBio Receive FDA Fast Track for BNT324/DB-1311 in Prostate Cancer
Details : BNT324/DB-1311 is a next-generation topoisomerase-I-inhibitor-based ADC candidate being investigated for metastatic castration-resistant prostate cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 24, 2024
Lead Product(s) : DB-1311
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : BioNTech
Deal Size : Inapplicable
Deal Type : Inapplicable
