Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Claseprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $288.0 million
Deal Type : Public Offering
Dianthus Announces Closing of its Upsized $288 Million Underwritten Public Offering
Details : The net proceeds will be used to advance the Company’s preclinical and clinical development activities, including DNTH103 (claseprubart), an investigational, long-acting monoclonal antibody.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 11, 2025
Lead Product(s) : Claseprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $288.0 million
Deal Type : Public Offering
Lead Product(s) : Claseprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $150.0 million
Deal Type : Public Offering
Dianthus Therapeutics, Inc. Announces Proposed $150 Million Underwritten Public Offering
Details : The net proceeds will be used to advance the Company’s preclinical and clinical development activities, including DNTH103 (claseprubart), an investigational, long-acting monoclonal antibody.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 08, 2025
Lead Product(s) : Claseprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $150.0 million
Deal Type : Public Offering
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Dianthus Completes Enrollment in DNTH103 Phase 2 MaGic Trial for MG
Details : DNTH103 is an investigational, potent mAb selectively target the classical pathway by inhibiting only the active form of the C1s protein, for treating myasthenia gravis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 05, 2025
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DNTH103 is a Antibody drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Polyradiculoneuropathy, Chronic Inflammatory Demyelinating.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 05, 2025
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Hesperos
Deal Size : Inapplicable
Deal Type : Inapplicable
Hesperos Supports Investigational Product for Phase II Trial with Human-on-a-Chip®
Details : DNTH103 is an investigational, potent mAb engineered to selectively targets by inhibiting only the active form of the C1s protein. It is being evaluated for generalized myasthenia gravis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 24, 2024
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Hesperos
Deal Size : Inapplicable
Deal Type : Inapplicable
A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
Details : DNTH103 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Polyneuropathies.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 05, 2024
Dianthus Therapeutics Gets FDA Clearance for Phase 2 Trial of DNTH103 in MMN
Details : DNTH103 is a potent monoclonal antibody engineered to selectively inhibitis only the active form of the C1s protein. It is being evaluated for the treatment of Multifocal Motor Neuropathy.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 12, 2024
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)
Details : DNTH103 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Myasthenia Gravis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 28, 2024
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Dianthus Initiates Phase 2 MaGic Trial Of DNTH103 in Myasthenia Gravis
Details : DNTH103 is an investigational, clinical-stage monoclonal antibody targeting the classical pathway by inhibiting the active form of C1s protein, evaluated for generalized myasthenia gravis.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 26, 2024
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Jefferies
Deal Size : $230.0 million
Deal Type : Private Placement
Dianthus Therapeutics Announces $230 Million Private Placement
Details : The net proceeds will be used for the clinical development of DNTH103. It is a selective inhibitor of the active C1s protein for the treatment of neuromuscular & autoimmune disorders.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
January 22, 2024
Lead Product(s) : DNTH103
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Jefferies
Deal Size : $230.0 million
Deal Type : Private Placement