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Inapplicable"},{"orgOrder":0,"company":"Akeso","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CHINA","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"Ebdarokimab","moa":"Undisclosed","graph1":"Dermatology","graph2":"Phase III","graph3":"Akeso","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Pre-Filled Injection","sponsorNew":"Akeso \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Akeso \/ Inapplicable"}]

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                          Details : ICP-488 is an oral, potent and selective TYK2 inhibitor, which is currently being evaluated for the treatment of moderate to severe plaque psoriasis.

                          Product Name : ICP-488

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : ICP-488

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The collaboration aims to advancing the MG-K10, a potential Best-in-Class therapy, a novel IL-4Rα-targeting antibody drug for atopic dermatitis and asthma.

                          Product Name : MG-K10

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          February 21, 2025

                          Lead Product(s) : MG-K10

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Hunan Mabgeek Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : AK111 (gumokimab) is an innovative, humanized IL-17 (interleukin-17) monoclonal antibody being developed for the treatment of autoimmune diseases such as psoriasis and ankylosing spondylitis.

                          Product Name : AK111

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 26, 2025

                          Lead Product(s) : Gumokimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : MG-K10, a humanized anti-IL-4Rα monoclonal antibody, is being investigated for treating Th2-mediated inflammatory diseases such as moderate-to-severe atopic dermatitis.

                          Product Name : MG-K10

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 03, 2025

                          Lead Product(s) : MG-K10

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Chime Biologics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Through the partnership, Tabuk will have exclusive rights to manufacture, distribute, and market the BAT2206 (ustekinumab), a biosimilar to Jansen's Stelara in Saudi Arabia.

                          Product Name : BAT2206

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          December 24, 2024

                          Lead Product(s) : Ustekinumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Tabuk Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          06

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : ASC40 (Denifanstat) is a FASN inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of acne vulgaris via oral tablet.

                          Product Name : ASC40

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Denifanstat

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : MH004 (tofacitinib etocomil) ointment 1.0%, a twice-daily pan-Jak inhibitor. It is being evaluated in late-stage clinical trial studies for the treating mild to moderate atopic dermatitis.

                          Product Name : MH004

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 29, 2024

                          Lead Product(s) : Tofacitinib Etocomil

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : ICP-332 is a potent and selective TYK2 inhibitor, which is being evaluated in the late-stage clinical trial studies to treat patients with moderate-to-severe atopic dermatitis.

                          Product Name : ICP-332

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : ICP-332

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : YY003 (botulinum toxin type A) is a liquid formulation that acts as SNAP25 inhibitor. It is currently being evaluated for the treatment of glabellar lines.

                          Product Name : YY003

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 25, 2024

                          Lead Product(s) : Botulinum Toxin A

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Claruvis Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : IBI112 (picankibart), an antibody, specifically binds to IL-23p19 inhibiting IL-23 receptor-mediated signaling pathway. It is being investigated in patients with moderate to severe plaque psoriasis.

                          Product Name : IBI112

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 27, 2024

                          Lead Product(s) : Picankibart

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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