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    [{"orgOrder":0,"company":"Ichnos Sciences","sponsor":"Glenmark Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"SWITZERLAND","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"Telazorlimab","moa":"OX40 receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Ichnos Sciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Ichnos Sciences \/ Glenmark Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"Ichnos Sciences \/ Glenmark Pharmaceuticals"},{"orgOrder":0,"company":"Torqur","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Bimiralisib","moa":"Pan-PI3K\/mTOR","graph1":"Dermatology","graph2":"Phase II","graph3":"Torqur","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Torqur \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Torqur \/ Inapplicable"},{"orgOrder":0,"company":"MoonLake Immunotherapeutics","sponsor":"Helix BioPharma","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"SWITZERLAND","productType":"Antibody","year":"2021","type":"Agreement","leadProduct":"Sonelokimab","moa":"IL-17A\/IL-17F receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"MoonLake Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"MoonLake Immunotherapeutics \/ Helix BioPharma","highestDevelopmentStatusID":"8","companyTruncated":"MoonLake Immunotherapeutics \/ Helix BioPharma"},{"orgOrder":0,"company":"MoonLake Immunotherapeutics","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"SWITZERLAND","productType":"Antibody","year":"2021","type":"Licensing Agreement","leadProduct":"Sonelokimab","moa":"IL-17A\/IL-17F receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"MoonLake Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"MoonLake Immunotherapeutics \/ Merck & Co","highestDevelopmentStatusID":"8","companyTruncated":"MoonLake Immunotherapeutics \/ Merck & Co"}]

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                            01

                            Torqur

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                            Lead Product(s) : Bimiralisib

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Torqur AG Presents Interim Phase 2 Clinical Trial Results

                            Details : Bimiralisib is a selective pan-PI3K/mTOR inhibitor, which is being evaluated for the topical treatment of actinic keratosis of the face or scalp.

                            Product Name : PQR309

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 07, 2025

                            Lead Product(s) : Bimiralisib

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Receives Positive Feedback On Sonelokimab Phase 3 Program

                            Details : M1095 (sonelokimab) is a humanized Nanobody® being evaluated for hidradenitis suppurativa treatment, consisting of three VHH domains linked by flexible spacers.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 26, 2024

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            MoonLake Immunotherapeutics Announces the Full Dataset from its 24-week MIRA Clinical Trial, Establishing the ...

                            Details : M1095 (sonelokimab) is a humanized nanobody consisting of three VHH domains covalently linked by flexible glycine-serine spacers. It selectively binds with IL-17A and IL-17F and inhibit IL-17A/A, IL-17A/F, and IL-17F/F dimer, which investigated for moder...

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 15, 2023

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $400.0 million

                            Deal Type : Public Offering

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                            MoonLake Immunotherapeutics Announces Pricing of $400 Million Upsized Public Offering of Class A Ordinary Shar...

                            Details : MoonLake intends to use the net proceeds to fund the ongoing advancement of M1095 (sonelokimab), a trivalent monomeric nanobody that neutralizes interleukins IL-17A, IL-17F, and IL-17A/F for the treatment of inflammatory diseases.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            June 28, 2023

                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $400.0 million

                            Deal Type : Public Offering

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                            05

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics Achieves Landmark Milestone with Positive Phase 2 Results for Nanobody Sonelokimab...

                            Details : M1095 (sonelokimab) is a humanized nanobody consisting of three VHH domains covalently linked by flexible glycine-serine spacers. It selectively binds with IL-17A and IL-17F and inhibit IL-17A/A, IL-17A/F, and IL-17F/F dimer, which investigated for hidra...

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 25, 2023

                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics Completes Patient Enrollment and Randomization Ahead of Schedule in A Phase 2 Tria...

                            Details : M1095 (sonelokimab) is a humanized nanobody® consisting of three VHH domains covalently linked by flexible glycine-serine spacers. It selectively binds with high affinity to IL-17A and IL-17F and inhibits IL-17A/A, IL-17A/F, and IL-17F/F dimers.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 02, 2023

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics Starts Phase 2 trial of The Nanobody® Sonelokimab in Patients with Moderate-to-Se...

                            Details : M1095 (sonelokimab) inhibits the naturally occurring IL-17A/A, IL-17A/F, and IL-17F/F dimers that drive inflammation. In addition, sonelokimab is designed to directly target sites of inflammation and penetrate difficult-to-reach inflamed tissues.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 05, 2022

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Vetter Pharma-Fertigung GmbH & Co

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics Signs Development and Manufacturing Agreement With Vetter Pharma International Gmb...

                            Details : Sonelokimab (M1095), is MoonLake’s investigational Nanobody® designed to treat inflammatory disease by inhibiting the naturally occurring IL-17A/A, IL-17A/F, and IL-17F/F dimers that drive inflammation.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 26, 2022

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Vetter Pharma-Fertigung GmbH & Co

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Helix BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics AG Announces Closing of Business Combination with Helix Acquisition Corp.

                            Details : MoonLake plans to execute on its development program to unlock the potential of Sonelokimab, the novel investigational Nanobody® for the treatment of inflammation, to revolutionize outcomes for patients with inflammatory diseases.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            May 04, 2022

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Helix BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            10

                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Helix BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics AG and Helix Acquisition Corp. Announce Business Combination Agreement to Create P...

                            Details : Proceeds from the transaction are expected to provide MoonLake with the capital needed to accelerate the development of the clinical stage, tri-specific Nanobody® sonelokimab, in multiple inflammatory diseases in dermatology and rheumatology driven by I...

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : $230.0 million

                            April 10, 2021

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Helix BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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