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[{"orgOrder":0,"company":"DelSiTech","sponsor":"DelSiTech","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"DelSiTech Enters into an Exclusive Licensing Agreement with Optifye Therapeutics for the Development of a Controlled Release Ophthalmic Eye Drop Product","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Preclinical","country":"FINLAND","productType":"Small molecule","productStatus":"Approved","date":"March 2022","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Preclinical"},{"orgOrder":0,"company":"DelSiTech","sponsor":"IVERIC bio","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"$1.2 million","newsHeadline":"Iveric Bio and DelSiTech Enter Exclusive Agreement for Development of Sustained Release Zimura\u00ae","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Preclinical","country":"FINLAND","productType":"Large molecule","productStatus":"New Molecular Entity","date":"July 2022","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Preclinical"},{"orgOrder":0,"company":"DelSiTech","sponsor":"Bill & Melinda Gates Foundation","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"DelSiTech Awarded a Grant to Develop Controlled and Sustained Release Injectables for Prophylactic HIV Vaccine","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Preclinical","country":"FINLAND","productType":"Vaccine","productStatus":"New Molecular Entity","date":"March 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical"},{"orgOrder":0,"company":"DelSiTech","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"DelSiTech Announces Positive Topline Clinical Data from Phase 1 Trial with its Sustained Release Eye Drop Platform","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Phase I","country":"FINLAND","productType":"Small molecule","productStatus":"New Molecular Entity","date":"June 2023","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Phase I"},{"orgOrder":0,"company":"DelSiTech","sponsor":"DRW Venture Capital LLC","pharmaFlowCategory":"D","amount":"$10.8 million","upfrontCash":"Undisclosed","newsHeadline":"DelSiTech Announces Closing of EUR 10 Million Financing Round to Advance its Silica-Based Drug Delivery Technology Platform","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Undisclosed","country":"FINLAND","productType":"Small molecule","productStatus":"Approved","date":"January 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed"}]

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            Details:

            The proceeds will be used to advance its unique, in-house, silica-based, drug delivery technology platform into clinical development, including DST1308 in Chronic Hepatitis B, as well as expanding its in-house manufacturing capability.

            Lead Product(s): Entecavir

            Therapeutic Area: Infections and Infectious Diseases Product Name: DST1308

            Highest Development Status: Undisclosed Product Type: Small molecule

            Partner/Sponsor/Collaborator: DRW Venture Capital LLC

            Deal Size: $10.8 million Upfront Cash: Undisclosed

            Deal Type: Financing January 16, 2024

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            DST-2105 is based on DelSiTech's Silica Matrix formulation technology which enables the once daily administration of eye drops in the cul-de-sac of the eye, which is investigated for relieving dry eye symptoms.

            Lead Product(s): DST-2105

            Therapeutic Area: Ophthalmology Product Name: DST-2105

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 29, 2023

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            DelSiTech will develop long-acting injectable formulations ensuring slow release of HIV vaccine. Silica Matrix technology provides controlled long-acting drug release w/o interfering with its therapeutic functions and is compatible with small molecules and large biologics.

            Lead Product(s): Undisclosed

            Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Bill & Melinda Gates Foundation

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Funding March 15, 2023

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            As part of Iveric Bio’s lifecycle expansion plan for Zimura (avacincaptad pegol), the Company is committed to developing sustained release technologies for the treatment of age-related macular degeneration (AMD).

            Lead Product(s): Avacincaptad Pegol

            Therapeutic Area: Ophthalmology Product Name: Zimura

            Highest Development Status: Preclinical Product Type: Large molecule

            Recipient: IVERIC bio

            Deal Size: Undisclosed Upfront Cash: $1.2 million

            Deal Type: Agreement July 05, 2022

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            Controlled release of dexamethasone eye drops, based on DelSiTech™ Silica Matrix technology, is a revolutionary eye drop product that is applied as a single drop, once daily under the eye lid which maintains therapeutic drug concentration in the eye.

            Lead Product(s): Dexamethasone

            Therapeutic Area: Ophthalmology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Recipient: Optifye Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement March 28, 2022

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