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                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Debiopharm has exercised its option to license SRB21, SunRock Biopharma's bispecific antibody, which targets both HER2 and HER3 human epidermal growth factor receptors.

                          Product Name : SRB21

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          September 30, 2025

                          Lead Product(s) : SRB21

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : SunRock Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Debio 1453P

                          Therapeutic Area : Undisclosed

                          Study Phase : Phase I

                          Sponsor : Biomedical Advanced Research and Development Authority | Wellcome Trust | Germany's Federal Ministry of Research, Technology and Space (BMFTR) | Global Antimicrobial Resistance Innovation Fund | Novo Nordisk Foundation (NNF)

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Debio 1453P is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 25, 2025

                          Lead Product(s) : Debio 1453P

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Biomedical Advanced Research and Development Authority | Wellcome Trust | Germany's Federal Ministry of Research, Technology and Space (BMFTR) | Global Antimicrobial Resistance Innovation Fund | Novo Nordisk Foundation (NNF)

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The collaboration aims to evaluate the feasibility of developing targeted radioligand therapies using Debiopharm’s proprietary AbYlink™ conjugation technology for Alkyon’s modular antibody platform.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 12, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Alkyon Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The grant will support the continued clinical development of Debio 1453, a first-in-class antibiotic with a novel mechanism of action to treat Neisseria gonorrhoeae infections.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          May 28, 2025

                          Lead Product(s) : Debio-1453

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : CARB-X

                          Deal Size : $20.2 million

                          Deal Type : Funding

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Debio 1562M is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Leukemia, Myeloid, Acute.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 13, 2025

                          Lead Product(s) : Debio 1562M

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Under the licensing agreement, Oncodesign will holds the rights of AbYlink technology aiming for drug discovery and preclinical services.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 24, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Oncodesign Services

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Debio 4126 is a Peptide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Acromegaly.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : Debio 4126

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Debio 0123 is an oral, potent, highly selective, and brain-penetrant WEE1 inhibitor is being evaluated with trodelvy for HR-positive/HER2-negative triple negative breast neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 25, 2025

                          Lead Product(s) : Debio 0123,Sacituzumab Govitecan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : MEDSIR

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Under the agreement, Debiopharm will advance the development of Debio 1453, a novel compound representing a new antibiotic class that targets Neisseria gonorrhoeae.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          January 14, 2025

                          Lead Product(s) : Debio 1453

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Gardp

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The funding will support the preclinical development of Debio 1453, a novel antibiotic specifically designed to combat Neisseria gonorrhoeae infections.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          November 21, 2024

                          Lead Product(s) : Debio 1453

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : CARB-X

                          Deal Size : $5.7 million

                          Deal Type : Funding

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