[{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Armata Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Microorganism","year":"2020","type":"Inapplicable","leadProduct":"AP-PA02","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"7","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Armata Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Microorganism","year":"2020","type":"Funding","leadProduct":"AP-PA02","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"7","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"SpliSense","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"ISRAEL","productType":"Oligonucleotide","year":"2024","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Solution for Nebulizer","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Calithera Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Funding","leadProduct":"CB-280","moa":"||Arginase","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"6","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Kinnear Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibiotic","year":"2021","type":"Funding","leadProduct":"CSA-131","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Anagram Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Oral","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Polyphor","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"SWITZERLAND","productType":"Peptide","year":"2020","type":"Funding","leadProduct":"Murepavadin","moa":"||Imp protein","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"6","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Anagram Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Beyond Air","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Funding","leadProduct":"Nitric Oxide","moa":"||sGC","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"10","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Anagram Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Agreement","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Undisclosed","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Oral","sponsorNew":"Cystic Fibrosis Foundation \/ Synspira Therapeutics","highestDevelopmentStatusID":"1","companyTruncated":"Cystic Fibrosis Foundation \/ Synspira Therapeutics"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Eloxx Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Funding","leadProduct":"Exaluren Sulfate","moa":"||CFTR","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Royalty Pharma","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Acquisition","leadProduct":"Ivacaftor","moa":"||CFTR","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cystic Fibrosis Foundation \/ Royalty Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Cystic Fibrosis Foundation \/ Royalty Pharma"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Pulmocide","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2021","type":"Funding","leadProduct":"Opelconazole","moa":"||CYP51","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Suspension for Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"BiomX","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"ISRAEL","productType":"Microorganism","year":"2022","type":"Funding","leadProduct":"BX004","moa":"||P. aeruginosa biofilm","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nasal Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"7","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Aridis Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Funding","leadProduct":"Gallium Citrate","moa":"||Bacterial growth","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal Aerosol","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Arcturus Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Oligonucleotide","year":"2023","type":"Funding","leadProduct":"ARCT-032","moa":"||CFTR","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal Solution for Nebulizer","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"4D Molecular Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Agreement","leadProduct":"4D-710","moa":"||CFTR","graph1":"Pulmonary\/Respiratory Diseases","graph2":"IND Enabling","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Aerosol","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"5","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Microbion","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Funding","leadProduct":"Pravibismane","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"IND Enabling","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Suspension for Inhalation","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"5","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"ContraFect Corporation","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Funding","leadProduct":"Exebacase","moa":"||26-kDa","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Peptilogics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Peptide","year":"2022","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"ReCode Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Nanite","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Prime Medicine","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Crestone","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Funding","leadProduct":"Inapplicable","moa":"||MmpL3","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Gensaic","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Discovery","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"2","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Cystic Fibrosis Foundation","sponsor":"Flagship Pioneering","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Partnership","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Discovery","graph3":"Cystic Fibrosis Foundation","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"2","companyTruncated":"Cystic Fibrosis Foundation \/ Cystic Fibrosis Foundation"}]

Find Clinical Drug Pipeline Developments & Deals by Cystic Fibrosis Foundation

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The proceeds will be used to accelerate ReCode’s gene correction research program with the goal of developing and commercializing new treatments for people with cystic fibrosis.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : ReCode Therapeutics

                          Deal Size : $15.0 million

                          Deal Type : Funding

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                          02

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The funding will support SpliSense to continue the clinical development of an inhaled antisense oligonucleotide drug SPL84 for treating patients suffering from cystic fibrosis.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          March 04, 2024

                          Lead Product(s) : SPL84,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Recipient : SpliSense

                          Deal Size : $8.5 million

                          Deal Type : Funding

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                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The net proceeds will be used to support the development of curative therapies by using Prime Editing to correct CFTR mutations at the natural genetic locus, for the treatment of Cystic Fibrosis (CF).

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 25, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Prime Medicine

                          Deal Size : $15.0 million

                          Deal Type : Funding

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The funding will advance ARCT-032, a novel messenger RNA (mRNA) therapeutic candidate formulated with Arcturus’ LUNAR® delivery technology for the treatment of Cystic Fibrosis.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          September 26, 2023

                          Lead Product(s) : ARCT-032,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Recipient : Arcturus Therapeutics

                          Deal Size : $25.0 million

                          Deal Type : Funding

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                          05

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Gensaic will use the net proceeds to develop full CFTR gene delivery to lung tissue using its proprietary phage-derived particle (PDP) platform in CFTR-based gene Therapy.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          September 01, 2023

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Discovery

                          Recipient : Gensaic

                          Deal Size : $3.5 million

                          Deal Type : Funding

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : If the therapy is successful, people with CF would be able to decrease the number of enzyme pills they must take to digest food properly from a handful of pills to only one per meal.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 04, 2023

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Anagram Therapeutics

                          Deal Size : $15.5 million

                          Deal Type : Funding

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : With the new funding from the Foundation, Nanite will work on initially developing polymer nanoparticles that can accurately deliver mRNA therapies to the lung while potentially better resisting the thick, sticky mucus that clogs the lungs of patients wi...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          March 15, 2023

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Nanite

                          Deal Size : $2.0 million

                          Deal Type : Funding

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : AR-501 is a novel, small molecule and an inhalable form of gallium citrate, which acts as an iron analog to starve bacteria of iron. Gallium is believed to inhibit multiple iron-dependent synthetic and metabolic pathways required for pathogenicity.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 12, 2022

                          Lead Product(s) : Gallium Citrate,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Aridis Pharmaceuticals

                          Deal Size : $12.5 million

                          Deal Type : Funding

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : BiomX has been given grant to support a clinical trial of BX004, a phage therapy to fight Pseudomonas aeruginosa infections in people with cystic fibrosis (CF). In lab experiments conducted by BiomX, BX004 killed antibiotic-resistant strains of P. aerugi...

                          Product Name : Undisclosed

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          May 01, 2022

                          Lead Product(s) : BX004,Inapplicable

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : BiomX

                          Deal Size : $5.0 million

                          Deal Type : Funding

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                          10

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The award provided by the Cystic Fibrosis Foundation will generate both in vitro and in vivo data about PLG0301 and PLG0206, which may potentially support an Investigational New Drug (IND) application with the FDA for its continued development.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          May 01, 2022

                          Lead Product(s) : PLG0301,Inapplicable

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Peptilogics

                          Deal Size : Undisclosed

                          Deal Type : Funding

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