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Affiliated Hospital of Shandong First Medical University | Tai\u2019an Central Hospital | Linyi People's Hospital | Rizhao People's","highestDevelopmentStatusID":"7","companyTruncated":"Shandong Qilu Stem Cells Engineering Co., Ltd. \/ Shandong Province Third Hospital | Dezhou People's Hospital | Children's Hospital Affiliated to Shandong University | The Second Affiliated Hospital of Shandong First Medical University | Tai\u2019an Central Hospital | Linyi People's Hospital | Rizhao People's"},{"orgOrder":0,"company":"Zhaoke Ophthalmology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"CHINA","productType":"Peptide, Unconjugated","year":"2025","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Zhaoke Ophthalmology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Gel","sponsorNew":"Zhaoke Ophthalmology \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Zhaoke Ophthalmology \/ Undisclosed"},{"orgOrder":0,"company":"German Center for Diabetes Research","sponsor":"Allergan","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2013","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Immunology","graph2":"Phase IV","graph3":"German Center for Diabetes Research","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Emulsion","sponsorNew":"German Center for Diabetes Research \/ Allergan","highestDevelopmentStatusID":"11","companyTruncated":"German Center for Diabetes Research \/ Allergan"},{"orgOrder":0,"company":"University Hospital Ghent","sponsor":"Funds for Research in Ophthalmology of Belgium | Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"BELGIUM","productType":"Peptide, Unconjugated","year":"2010","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"University Hospital Ghent","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"University Hospital Ghent \/ Funds for Research in Ophthalmology of Belgium | Novartis Pharmaceuticals Corporation","highestDevelopmentStatusID":"11","companyTruncated":"University Hospital Ghent \/ Funds for Research in Ophthalmology of Belgium | Novartis Pharmaceuticals Corporation"},{"orgOrder":0,"company":"Fraunhofer-Institute of Toxicology and Experimental Medicine","sponsor":"AstraZeneca","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2018","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Undisclosed","graph2":"Undisclosed","graph3":"Fraunhofer-Institute of Toxicology and Experimental Medicine","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Fraunhofer-Institute of Toxicology and Experimental Medicine \/ AstraZeneca","highestDevelopmentStatusID":"1","companyTruncated":"Fraunhofer-Institute of Toxicology and Experimental Medicine \/ AstraZeneca"},{"orgOrder":0,"company":"NeuroVive Pharmaceutical AB","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"SWEDEN","productType":"Peptide, Unconjugated","year":"2013","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase II","graph3":"NeuroVive Pharmaceutical AB","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"NeuroVive Pharmaceutical AB \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"NeuroVive Pharmaceutical AB \/ Undisclosed"},{"orgOrder":0,"company":"Pari","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2011","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase III","graph3":"Pari","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Pari \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Pari \/ Undisclosed"},{"orgOrder":0,"company":"Novaliq","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Novaliq","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Novaliq \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Novaliq \/ Undisclosed"},{"orgOrder":0,"company":"Novaliq","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Novaliq","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Novaliq \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Novaliq \/ Undisclosed"},{"orgOrder":0,"company":"Novaliq","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2017","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Novaliq","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Novaliq \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Novaliq \/ Undisclosed"},{"orgOrder":0,"company":"Novaliq","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"GERMANY","productType":"Peptide, Unconjugated","year":"2015","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Novaliq","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Novaliq \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Novaliq \/ Undisclosed"},{"orgOrder":0,"company":"Leo Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"DENMARK","productType":"Peptide, Unconjugated","year":"2018","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Dermatology","graph2":"Phase IV","graph3":"Leo Pharma","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leo Pharma \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Leo Pharma \/ Undisclosed"},{"orgOrder":0,"company":"F2G Limited","sponsor":"Bio-Kinetic Europe","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Peptide, Unconjugated","year":"2017","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"F2G Limited","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"F2G Limited \/ Bio-Kinetic Europe","highestDevelopmentStatusID":"6","companyTruncated":"F2G Limited \/ Bio-Kinetic Europe"},{"orgOrder":0,"company":"OphRx","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase I","graph3":"OphRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"OphRx \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"OphRx \/ Undisclosed"},{"orgOrder":0,"company":"University of Waterloo","sponsor":"Sun Pharmaceutical Industries Limited","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"CANADA","productType":"Peptide, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"University of Waterloo","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"University of Waterloo \/ Sun Pharmaceutical Industries Limited","highestDevelopmentStatusID":"1","companyTruncated":"University of Waterloo \/ Sun Pharmaceutical Industries Limited"},{"orgOrder":0,"company":"Boston Sight","sponsor":"Allergan","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Ophthalmology","graph2":"Phase I\/ Phase II","graph3":"Boston Sight","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Insert","sponsorNew":"Boston Sight \/ Allergan","highestDevelopmentStatusID":"7","companyTruncated":"Boston Sight \/ Allergan"},{"orgOrder":0,"company":"European Society for Blood and Marrow Transplantation","sponsor":"Novartis Pharmaceuticals Corporation | Pfizer Inc","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"","productType":"Peptide, Unconjugated","year":"2014","type":"Inapplicable","leadProduct":"Cyclosporine","moa":"Cyclophilin A","graph1":"Hematology","graph2":"Phase III","graph3":"European Society for Blood and Marrow Transplantation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"European Society for Blood and Marrow Transplantation \/ Novartis Pharmaceuticals Corporation | Pfizer Inc","highestDevelopmentStatusID":"10","companyTruncated":"European Society for Blood and Marrow Transplantation \/ Novartis Pharmaceuticals Corporation | Pfizer Inc"},{"orgOrder":0,"company":"Concord Biotech","sponsor":"Lupin Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"INDIA","productType":"Antibiotic","year":"2020","type":"Inapplicable","leadProduct":"Mycophenolate Mofetil","moa":"||Inosine-5'-monophosphate dehydrogenase (IMPDH)","graph1":"Immunology","graph2":"Approved FDF","graph3":"Concord Biotech","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Concord Biotech \/ Lupin Ltd","highestDevelopmentStatusID":"15","companyTruncated":"Concord Biotech \/ Lupin Ltd"},{"orgOrder":0,"company":"Lupin Ltd","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"INDIA","productType":"Antibiotic","year":"2020","type":"Inapplicable","leadProduct":"Mycophenolate Mofetil","moa":"||Inosine-5'-monophosphate dehydrogenase (IMPDH)","graph1":"Immunology","graph2":"Approved FDF","graph3":"Lupin Ltd","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Lupin Ltd \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Lupin Ltd \/ Undisclosed"},{"orgOrder":0,"company":"Medsenic","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"FRANCE","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Arsenic Trioxide","moa":"||Thioredoxin reductase 1","graph1":"Immunology","graph2":"Phase III","graph3":"Medsenic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Medsenic \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Medsenic \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for Cyclosporin

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Cyclosporine is a Peptide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Conjunctivitis, Allergic.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          May 10, 2010

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Cyclosporine is a Peptide drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          June 18, 2025

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Cyclosporine A is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          April 24, 2025

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Cyclosporine is a Peptide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Cyclosporine is a Peptide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Anemia, Aplastic.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          December 31, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Incyte Corporation

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Vevye is an approved cyclosporine ophthalmic solution, designed to address unmet needs, providing patients with a fast acting and well tolerable dry eye drug therapy.

                          Product Name : Vevye

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          November 12, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Institute of Hematology & Blood Diseases Hospital, China

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Institute of Hematology & Blood Diseases Hospital, China

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Cyclosporine is a Peptide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Anemia, Aplastic.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          September 26, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Qilu Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The companies will work to develop SGN’s MNP platform-based Cyclosporine formulation for use with Eyenovia’s Optejet dispenser for treatment of chronic dry eye disease.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Undisclosed

                          July 30, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : SGN Nanopharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Vevizye is a clear ciclosporin 0.1% solution, free of oils, surfactants, and preservatives. It is indicated for the treatment of moderate to severe dry eye disease.

                          Product Name : CyclASol

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          July 29, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement aims for the registration and marketing of Cyclosporine Ophthalmic Nanoemulsion, generic of Restasis, in Mexico.

                          Product Name : Restasis-Generic

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Undisclosed

                          July 22, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Lupin Ltd

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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