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Vaccine","sponsor":"Janus Henderson Investors","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Series A Financing","leadProduct":"Amezosvatein","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Curevo Vaccine","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.029999999999999999,"dosageForm":"Injection","sponsorNew":"Curevo Vaccine \/ Janus Henderson Investors","highestDevelopmentStatusID":"8","companyTruncated":"Curevo Vaccine \/ Janus Henderson Investors"},{"orgOrder":0,"company":"Curevo Vaccine","sponsor":"Medicxi","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2025","type":"Series B Financing","leadProduct":"Amezosvatein","moa":"Undisclosed","graph1":"Infections and Infectious 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Vaccine","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Curevo Vaccine \/ Curevo Vaccine","highestDevelopmentStatusID":"8","companyTruncated":"Curevo Vaccine \/ Curevo Vaccine"}]

Find Clinical Drug Pipeline Developments & Deals by Curevo Vaccine

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : GC Biopharma will be responsible for producing a portion of the commercial supply of CRV-101 (amezosvatein), , a recombinant shingles vaccine currently under clinical development.

                          Product Name : CRV-101

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          October 13, 2025

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : GC Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of company's mid-stage product CRV-101 (amezosvatein). It is being evaluated to prevent shingles.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          March 17, 2025

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Medicxi

                          Deal Size : $110.0 million

                          Deal Type : Series B Financing

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                          03

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : CRV-101 (amezosvatein) uses an adjuvant targeting the TLR4 pathway to boost the immune response to the gE antigen. Currently being investigated for Shingles in 50 years and older.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 12, 2025

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : CRV-101 (amezosvatein) is a non-mRNA, adjuvanted subunit vaccine, which is under phase 2 clinical development for the prevention of Herpes Zoster in adults aged 50 years and older.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 07, 2024

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : CRV-101 is a clinical-stage adjuvanted sub-unit vaccine under investigation for the prevention of shingles in older adults. Shingles is a painful blistering skin rash caused by a reactivation of the varicella zoster virus.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          November 16, 2022

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Janus Henderson Investors

                          Deal Size : $26.0 million

                          Deal Type : Series A Financing

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                          06

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : CRV-101 is for the prevention of shingles in older adults. CRV-101 was specifically designed with a goal of producing an optimal immune response while using a smaller amount of adjuvant with the goal to create a vaccine with good tolerability and a simil...

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 15, 2022

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : Mogam Biotechnology Research Institute | Green Cross Lab Cell

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Amezosvatein is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Herpes Zoster.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          March 31, 2022

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Mogam Biotechnology Research Institute | Green Cross Lab Cell

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Details : The administration of Curevo’s adjuvanted sub-unit Shingles investigational vaccine resulted in a robust antibody response against a key component (gE) of the shingles virus at 1 month after 2nd vaccination, and at one year.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          September 15, 2020

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Neuroscience
                          Not Confirmed
                          Neuroscience
                          Not Confirmed

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase I

                          Sponsor : Access to Advanced Health Institute | Mogam Biotechnology Research Institute | Green Cross Lab Cell

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Amezosvatein is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Herpes Zoster.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 29, 2019

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Access to Advanced Health Institute | Mogam Biotechnology Research Institute | Green Cross Lab Cell

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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