
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : GC Biopharma
Deal Size : Undisclosed
Deal Type : Agreement
Gc Biopharma Acquires CMO Rights for Shingles Vaccine from Curevo Vaccine
Details : GC Biopharma will be responsible for producing a portion of the commercial supply of CRV-101 (amezosvatein), , a recombinant shingles vaccine currently under clinical development.
Product Name : CRV-101
Product Type : Vaccine
Upfront Cash : Undisclosed
October 13, 2025
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : GC Biopharma
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Medicxi
Deal Size : $110.0 million
Deal Type : Series B Financing
Curevo Raises $110 Million to Advance Amezosvatein Shingles Vaccine
Details : The financing aims to advance the clinical development of company's mid-stage product CRV-101 (amezosvatein). It is being evaluated to prevent shingles.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
March 17, 2025
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Medicxi
Deal Size : $110.0 million
Deal Type : Series B Financing

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Curevo Announces Positive Updated Phase 2 Data for Amezosvatein Shingles Vaccine
Details : CRV-101 (amezosvatein) uses an adjuvant targeting the TLR4 pathway to boost the immune response to the gE antigen. Currently being investigated for Shingles in 50 years and older.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
January 12, 2025
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Curevo Vaccine Reports Positive Phase 2 Results for Amezosvatein, a Shingles Vaccine
Details : CRV-101 (amezosvatein) is a non-mRNA, adjuvanted subunit vaccine, which is under phase 2 clinical development for the prevention of Herpes Zoster in adults aged 50 years and older.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
January 07, 2024
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Janus Henderson Investors
Deal Size : $26.0 million
Deal Type : Series A Financing
Details : CRV-101 is a clinical-stage adjuvanted sub-unit vaccine under investigation for the prevention of shingles in older adults. Shingles is a painful blistering skin rash caused by a reactivation of the varicella zoster virus.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
November 16, 2022
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Janus Henderson Investors
Deal Size : $26.0 million
Deal Type : Series A Financing

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Curevo Vaccine Announces Enrollment Complete in Phase 2b Trial of CRV-101 Vaccine Against Shingles
Details : CRV-101 is for the prevention of shingles in older adults. CRV-101 was specifically designed with a goal of producing an optimal immune response while using a smaller amount of adjuvant with the goal to create a vaccine with good tolerability and a simil...
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
September 15, 2022
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Mogam Biotechnology Research Institute | Green Cross Lab Cell
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Amezosvatein is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Herpes Zoster.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
March 31, 2022
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Mogam Biotechnology Research Institute | Green Cross Lab Cell
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The administration of Curevo’s adjuvanted sub-unit Shingles investigational vaccine resulted in a robust antibody response against a key component (gE) of the shingles virus at 1 month after 2nd vaccination, and at one year.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
September 15, 2020
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Access to Advanced Health Institute | Mogam Biotechnology Research Institute | Green Cross Lab Cell
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety, Tolerability, and Immunogenicity of CRV-101 in Healthy Adult Subjects
Details : Amezosvatein is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Herpes Zoster.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
January 29, 2019
Lead Product(s) : Amezosvatein
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Access to Advanced Health Institute | Mogam Biotechnology Research Institute | Green Cross Lab Cell
Deal Size : Inapplicable
Deal Type : Inapplicable

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