
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved FDF
Sponsor : USHV
Deal Size : Undisclosed
Deal Type : Collaboration
Corstasis, U.S. Heart and Vascular to Improve Heart Failure Care with Enbumyst
Details : Corstasis and USHV to co-develop value-based care for outpatient fluid overload in CHF, liver, and kidney disease using Enbumyst (bumetanide nasal spray).
Product Name : Enbumyst
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 25, 2025
Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved FDF
Sponsor : USHV
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved FDF
Sponsor : Aptar Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Aptar Pharma’s Unidose System Delivers FDA-Approved Intranasal Diuretic
Details : Enbumyst (bumetanide) appears to block the active reabsorption of chloride and possibly sodium, resulting in excretion of sodium, chloride, and water and, hence, diuresis.
Product Name : Enbumyst
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 18, 2025
Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved FDF
Sponsor : Aptar Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Corstasis' FDA-Approved Bumetanide Nasal Spray NDA
Details : RSQ-777 (bumetanide is given to help treat edema and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 27, 2025
Lead Product(s) : Bumetanide
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
