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Find Clinical Drug Pipeline Developments & Deals by Corino Therapeutics


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            Lead Product(s): Tolcapone

            Therapeutic Area: Genetic Disease Product Name: CRX-1008

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 15, 2020


            The results confirm that CRX-1008 is a potent TTR stabilizer in both plasma and CSF using established ex vivo assays. CRX-1008 normalized TTR concentration in plasma with an overall mean increase in plasma TTR tetramer concentration of 55%.