[{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2022","type":"Inapplicable","leadProduct":"Exebacase","moa":"26-kDa","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ContraFect Corporation \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Exebacase","moa":"26-kDa","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ContraFect Corporation \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2022","type":"Inapplicable","leadProduct":"Exebacase","moa":"26-kDa","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ContraFect Corporation \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Exebacase","moa":"26-kDa","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ContraFect Corporation \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious 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Foundation","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Funding","leadProduct":"Exebacase","moa":"26-kDa","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ContraFect Corporation \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"4","companyTruncated":"ContraFect Corporation \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Exebacase","moa":"Cell wall peptidoglycan synthesis","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Microorganism","year":"2022","type":"Inapplicable","leadProduct":"CF-296","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"ContraFect Corporation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Implant","sponsorNew":"ContraFect Corporation \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"ContraFect Corporation \/ Inapplicable"},{"orgOrder":0,"company":"ContraFect Corporation","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious 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                          01

                          Legal Affairs
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                          Details : CF-370 will be the first engineered lysin therapeutic targeting Gram-negative pathogens to enter a human clinical trial for hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia.

                          Product Name : CF-370

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          October 16, 2023

                          Lead Product(s) : CF-370

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Legal Affairs
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                          Legal Affairs
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                          Details : The IND application supports a proposed indication for its intravenous (IV) antibacterial agent, CF-370, for treatment of hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP).

                          Product Name : CF-370

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 18, 2023

                          Lead Product(s) : CF-370

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Legal Affairs
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                          Legal Affairs
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                          Details : The company intends to use the net proceeds to support ongoing enrollment of patients in the Phase 1b/2 clinical study of intra-articular CF-301 (exebacase), a first-in-class direct lytic agent, for the treatment of chronic prosthetic joint infections of...

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          June 27, 2023

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : $9.6 million

                          Deal Type : Financing

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                          04

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : CF-301 (exebacase) is a lysin with potent activity against staphylococcus aureus ("Staph aureus"). It has the potential to be the first-in-class of a new treatment for chronic prosthetic joint infections of the knee.

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          April 26, 2023

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : CF-301 (exebacase) is a lysin with potent activity against staphylococcus aureus ("Staph aureus"). Exebacase has the potential to be the first-in-class of a new treatment for patients with Staph aureus bacteremia.

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          March 04, 2023

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : CF-301 (exebacase) is a lysin and member of a new class of targeted protein-based antimicrobials that has demonstrated activity against S. aureus in laboratory (in vitro) and animal studies, alone and in addition to conventional antibiotics.

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          December 19, 2022

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : CF-301 (exebacase) is a lysin and member of a new class of targeted protein-based antimicrobials that has demonstrated activity against S. aureus in laboratory (in vitro) and animal studies, alone and in addition to conventional antibiotics.

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          December 13, 2022

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Maxim Group LLC

                          Deal Size : $7.0 million

                          Deal Type : Public Offering

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                          08

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : Company’s lysins, exebacase and CF-296, as additional agents in the treatment armamentarium against bone and joint infections due to their in vitro activity against coagulase-negative staphylococci, and their potential for both local and systemic anti-...

                          Product Name : CF-296

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          December 09, 2022

                          Lead Product(s) : CF-296

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : The positive clinical data demonstrated in these patients underpins the potential to prosecute CF-301 (exebacase) in a blinded clinical study of patients with chronic or recurrent prosthetic joint infections caused by MRSA or coagulase-negative Staph.

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          December 09, 2022

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Legal Affairs
                          Not Confirmed
                          Legal Affairs
                          Not Confirmed

                          Details : The Phase 1b/2 study of exebacase is a randomized, double-blind, placebo-controlled study to assess the efficacy and safety of exebacase in the setting of an arthroscopic DAIR procedure in patients with chronic PJI of the knee due t o S. aureus and/or Co...

                          Product Name : CF-301

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          November 28, 2022

                          Lead Product(s) : Exebacase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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