Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Constant Announces First Patient Dosed in Phase 2 Trial of TXA127 for Stroke Recovery
Details : TXA127 (talfirastide) is a pharmaceutical formulation of the naturally occurring human peptide angiotensin-(1‐7). It is under phase 2 clinical development for ischemic stroke recovery.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
September 01, 2024
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Talfirastide
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 2 Study of TXA127 in Post-ischemic Stroke Patients
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
November 18, 2023
Lead Product(s) : Talfirastide
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Talfirastide
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
TXA127 in Non-Ambulant Patients With DMD Cardiomyopathy
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
August 28, 2023
Lead Product(s) : Talfirastide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The trial will test several compounds, each against a placebo group. The TXA127 segment will involve 300 patients treated with the peptide and will be conducted at some 60 sites nationwide.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
December 05, 2021
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Researchers at two major medical centers in Israel, Rambam Medical Health Care Campus and Ziv Medical Center, have initiated a Phase 2 clinical trial of a promising new treatment for COVID-19. These trials are testing TXA27, a compound with an establishe...
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
February 24, 2021
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : Rambam Health Care Campus
Deal Size : Inapplicable
Deal Type : Inapplicable
Angiotensin 1-7 as a Therapy in the Treatment of COVID-19
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
October 28, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : Rambam Health Care Campus
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Constant Therapeutics' TXA127 to be Tested in Multiple Clinical Trials for COVID-19 Patients
Details : Constant Therapeutics' peptide drug TXA127 will be tested in a series of Phase 2 clinical trials in hospitalized COVID-19 patients who are not in the Intensive Care Unit (ICU).
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
August 07, 2020
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Constant Therapeutics Announces Start of Phase 2 Trial of Peptide Drug TXA127 for COVID-19
Details : The double-blind, placebo-controlled trial will recruit 100 patients with COVID-19 who require oxygen but are not in the ICU. The endpoints include incidence of renal failure and incidence of respiratory failure.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
July 29, 2020
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : Columbia University
Deal Size : Inapplicable
Deal Type : Inapplicable
TXA127 for the Treatment of Severe COVID-19
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
May 26, 2020
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : Columbia University
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Tarix Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
TXA127 in Enhancement of Engraftment in Adult Double Cord Blood Transplantation
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
February 21, 2011
Lead Product(s) : Angiotensin (1-7)
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Tarix Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable