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            CC-42344 is a novel, broad-spectrum PB2 inhibitor, investigational antiviral candidate, which is being evaluated for the treatment of pandemic and seasonal influenza A.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 19, 2024

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            CC-42344 is a oral small molecule PB2 inhibitor which is being evaluated for the treatment of pandemic and seasonal influenza A in phase 2 clinical trials.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 31, 2023

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            CDI-988, a novel, oral, broad-spectrum 3CL protease inhibitor, receives HREC approval to conduct a Phase 1 study for the potential treatment for COVID-19.

            Lead Product(s): CDI-988

            Therapeutic Area: Infections and Infectious Diseases Product Name: CDI-988

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 28, 2023

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            CDI-988, a novel, oral, broad-spectrum 3CL protease inhibitor, receives HREC approval to conduct a Phase 1 study for the potential treatment for COVID-19.

            Lead Product(s): CDI-988

            Therapeutic Area: Infections and Infectious Diseases Product Name: CDI-988

            Highest Development Status: IND Enabling Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 31, 2023

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            The proceeds will be used in its influenza A program, in which the Company is preparing to file with the United Kingdom regulatory agency to begin a Phase 2a human challenge study with its oral PB2 inhibitor CC-42344.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Phillip Frost

            Deal Size: $4.0 million Upfront Cash: Undisclosed

            Deal Type: Private Placement April 10, 2023

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            In vitro testing showed CC-42344’s excellent antiviral activity against influenza A strains, including pandemic and seasonal strains, as well as against strains resistant to Tamiflu® and Xofluza®, while also demonstrating favorable PK and safety profiles.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 19, 2022

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            CC-42344, an oral PB2 inhibitor, is specifically designed to be effective against all significant pandemic and seasonal influenza A strains and to have a high barrier to resistance due to the way the virus’ replication machinery is targeted.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 17, 2022

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            CC-42344 is an oral PB2 inhibitor, is specifically designed to be effective against all significant pandemic and seasonal influenza A strains and to have high barrier to resistance due to the way the virus’ replication machinery is targeted.

            Lead Product(s): CC-42344,Favipiravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: IND Enabling Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 01, 2022

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            CC-42344 is an oral PB2 inhibitor specifically designed to be effective against all significant pandemic and seasonal influenza A strains and to have a high barrier to resistance due to the way the virus’ replication machinery is targeted.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 26, 2022

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            CC-42344 is an oral PB2 inhibitor that blocks essential step of viral replication, is specifically designed to be effective against all significant pandemic and seasonal influenza A strains and to have high barrier to resistance due to way virus’ machinery is targeted.

            Lead Product(s): CC-42344

            Therapeutic Area: Infections and Infectious Diseases Product Name: CC-42344

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 08, 2022

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