Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Vemurafenib,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : University of Manchester | University of Birmingham | Royal Marsden NHS Foundation Trust | F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 14, 2023
Lead Product(s) : Vemurafenib,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : University of Manchester | University of Birmingham | Royal Marsden NHS Foundation Trust | F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : T3011,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
T3011 in Combination With Cobimetinib in Patients With Advanced Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Microorganism
Upfront Cash : Inapplicable
March 06, 2023
Lead Product(s) : T3011,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ifebemtinib,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Hyfinity Investments
Deal Size : $15.0 million
Deal Type : Series B Financing
Details : InxMed will use the funds to accelerate ongoing clinical trials of IN10018 (BI 853520) for multiple cancer types in both US and China, including the initiation of pivotal trials, and advance more stroma targeting pipelines into clinics in both US and Chi...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 05, 2022
Lead Product(s) : Ifebemtinib,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Hyfinity Investments
Deal Size : $15.0 million
Deal Type : Series B Financing
Lead Product(s) : T3011,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Agreement
Details : MVR-T3011, ImmVira's proprietary 3-in-1oncolytic herpes simplex virus ("oHSV"), is a novel genetically engineered oHSV which aims to achieve the most favorable profile of attenuated HSV-1 with replication potency in tumor cells.
Product Name : Undisclosed
Product Type : Microorganism
Upfront Cash : Undisclosed
April 19, 2022
Lead Product(s) : T3011,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Alectinib Hydrochloride,Alpelisib,Anastrozole,Atezolizumab,Bevacizumab,Capecitabine,Carboplatin,Cobimetinib,Entrectinib,Eribulin,Fulvestrant,Hyaluronidase,Pertuzumab,Trastuzumab,Irinotecan Hydrochloride,Letrozole,Paclitaxel,Niraparib Tosylate,Olaparib,Palbociclib,Trastuzumab Emtansine,Vemurafenib,Vinorelbine Tartrate,Vismodegib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Genentech | Oregon Health and Science University
Deal Size : Inapplicable
Deal Type : Inapplicable
SMMART Adaptive Clinical Treatment (ACT) Trial
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 14, 2022
Lead Product(s) : Alectinib Hydrochloride,Alpelisib,Anastrozole,Atezolizumab,Bevacizumab,Capecitabine,Carboplatin,Cobimetinib,Entrectinib,Eribulin,Fulvestrant,Hyaluronidase,Pertuzumab,Trastuzumab,Irinotecan Hydrochloride,Letrozole,Paclitaxel,Niraparib Tosylate,Olaparib,Palbociclib,Trastuzumab Emtansine,Vemurafenib,Vinorelbine Tartrate,Vismodegib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Genentech | Oregon Health and Science University
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cobimetinib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable
Cobimetinib In Extracranial Arteriovenous Malformations (COBI-AVM Study)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 18, 2021
Lead Product(s) : Cobimetinib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Peg L asparaginase,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Oregon Health and Science University | Genentech | Servier
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
September 05, 2021
Lead Product(s) : Peg L asparaginase,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Oregon Health and Science University | Genentech | Servier
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cobimetinib,Vemurafenib,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Clinical Research Technology
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 25, 2021
Lead Product(s) : Cobimetinib,Vemurafenib,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Clinical Research Technology
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Vociprotafib,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The ongoing Phase 1b/2 RMC-4630-02 trial is designed to evaluate the safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of RMC-4630 and cobimetinib in adult patients with relapsed/refractory solid tumors that harbor specific genomic mut...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 10, 2020
Lead Product(s) : Vociprotafib,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ifebemtinib,Cobimetinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The combination of KRAS G12C inhibitors and IN10018 induced FAK signaling by KRAS G12C inhibition, serving as one predominant mechanism of drug resistance of KRAS G12C inhibition, and IN10018 significantly decreases the FAK signaling induced by KRAS G12C...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 23, 2020
Lead Product(s) : Ifebemtinib,Cobimetinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable