[{"orgOrder":0,"company":"Chase Therapeutics","sponsor":"Chinalink Asia Holdings","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Series B Financing","leadProduct":"Pramipexole DiHCl","moa":"D2 receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Chase Therapeutics","amount2":0.02,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0.02,"dosageForm":"Oral Tablet, Immediate Release","sponsorNew":"Chase Therapeutics \/ Chinalink Asia Holdings","highestDevelopmentStatusID":"8","companyTruncated":"Chase Therapeutics \/ Chinalink Asia Holdings"},{"orgOrder":0,"company":"Chase Therapeutics","sponsor":"Alto Neuroscience","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Acquisition","leadProduct":"Pramipexole Dihydrochloride","moa":"||D2 receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Chase Therapeutics","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0.070000000000000007,"dosageForm":"Oral Tablet","sponsorNew":"Chase Therapeutics \/ Alto Neuroscience","highestDevelopmentStatusID":"8","companyTruncated":"Chase Therapeutics \/ Alto Neuroscience"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          ACS Fall 2025
                          Not Confirmed
                          ACS Fall 2025
                          Not Confirmed

                          Details : Alto gains a portfolio of potentially best-in-class dopamine agonist, including ALTO-207, a fixed-dose combination of pramipexole and ondansetron, for treatment resistant depression.

                          Product Name : ALTO-207

                          Product Type : Other Small Molecule

                          Upfront Cash : $1.7 million

                          June 03, 2025

                          Lead Product(s) : Pramipexole Dihydrochloride,Ondansetron

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II

                          Sponsor : Alto Neuroscience

                          Deal Size : $73.2 million

                          Deal Type : Acquisition

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                          02

                          ACS Fall 2025
                          Not Confirmed
                          ACS Fall 2025
                          Not Confirmed

                          Details : The proceeds will support Phase 3 pivotal trials for CTC-501 for the treatment of Major Depressive Disorder (MDD) and CTC-413 for the treatment of Parkinson’s Disease (PD) as well as completion of the development and validation of a diagnostic product ...

                          Product Name : CTC-501

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          October 20, 2021

                          Lead Product(s) : Pramipexole DiHCl

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II

                          Sponsor : Chinalink Asia Holdings

                          Deal Size : $20.0 million

                          Deal Type : Series B Financing

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