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    [{"orgOrder":0,"company":"Cerevance","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Solengepras","moa":"G-protein coupled receptor 6 (GPR6)||GPR6","graph1":"Neurology","graph2":"Phase III","graph3":"Cerevance","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Cerevance \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cerevance \/ Undisclosed"},{"orgOrder":0,"company":"Cerevance","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Solengepras","moa":"G-protein coupled receptor 6 (GPR6)||GPR6","graph1":"Neurology","graph2":"Phase III","graph3":"Cerevance","amount2":0,"highestDevelopmentShortName":"Ph 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Undisclosed"},{"orgOrder":0,"company":"Cerevance","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Solengepras","moa":"G-protein coupled receptor 6 (GPR6)||GPR6","graph1":"Neurology","graph2":"Phase III","graph3":"Cerevance","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cerevance \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cerevance \/ Undisclosed"},{"orgOrder":0,"company":"Cerevance","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Solengepras","moa":"G-protein coupled receptor 6 (GPR6)||GPR6","graph1":"Undisclosed","graph2":"Phase I","graph3":"Cerevance","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals by Cerevance

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                            01

                            Cerevance

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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cerevance Doses First Patient in Phase 3 ARISE Trial for Parkinson’s Disease

                            Details : CVN424 (solengepras) is a first-in-class non-dopamine therapy that selectively modulates GPR6, being investigated for the treatment option for individuals with early-stage Parkinson’s disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 18, 2024

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Cerevance

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : CVN293

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cerevance’s CVN293 Demonstrated Positive Phase 1 Results in Healthy Volunteers

                            Details : CVN293 is designed to inhibit KCNK13, a potentially novel target involved in activating the NLRP3 inflammasome. It is being evaluated for the treatment of frontotemporal dementia.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 11, 2024

                            Lead Product(s) : CVN293

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : $1,125.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Cerevance Achieves Second Milestone in Research Collaboration with Merck

                            Details : The collaboration focuses on the identification and validation of novel therapeutic targets for Alzheimer’s disease using NETSseq platform.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $25.0 million

                            October 08, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : $1,125.0 million

                            Deal Type : Collaboration

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                            04

                            Cerevance

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

                            Details : CVN424 is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Parkinson Disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 14, 2024

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Cerevance

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                            AIChE Annual Meeting
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                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery

                            Sponsor : Merck & Co

                            Deal Size : $1,125.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Cerevance Achieves First Milestone in Research Collaboration with Merck

                            Details : Through the research collaboration, Cerevance is concentrating on identifying novel therapeutic candidates for the treatment of patients with alzheimer's disease.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $25.0 million

                            May 02, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery

                            Sponsor : Merck & Co

                            Deal Size : $1,125.0 million

                            Deal Type : Collaboration

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                            06

                            Cerevance

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                            AIChE Annual Meeting
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                            Cerevance

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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Agent Capital

                            Deal Size : $98.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Cerevance Adds $47 Million in Series B-1 Extension to Advance Robust Clinical Pipeline

                            Details : The financing is intended to support the clinical development of CVN424, which is being investigated as a treatment option for individuals with early-stage Parkinson’s disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            April 25, 2024

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Agent Capital

                            Deal Size : $98.0 million

                            Deal Type : Series B Financing

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                            07

                            Cerevance

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                            AIChE Annual Meeting
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                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cerevance Doses First Patient in ASCEND Phase 2 Clinical Study of CVN424, a First-in-Class, Non-Dopaminergic T...

                            Details : CVN424 is a first-in-class non-dopamine therapy that selectively modulates GPR6, an orphan G-protein coupled receptor, which is investigated for the treatment option for individuals with early-stage Parkinson’s disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 13, 2023

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Cerevance

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                            AIChE Annual Meeting
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                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : CVN293

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cerevance Doses First Subject in Phase 1 Clinical Study of CVN293, a Selective Inhibitor of KCNK13 Designed to...

                            Details : CVN293 is an investigational, potent, and selective inhibitor of KCNK13 and has been implicated in many neurodegenerative diseases, including Amyotrophic Lateral Sclerosis, Alzheimer’s disease and severe age-related macular degeneration.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 19, 2023

                            Lead Product(s) : CVN293

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Cerevance

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                            AIChE Annual Meeting
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                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Early Parkinson's Disease Monotherapy With CVN424

                            Details : CVN424 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Parkinson Disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 23, 2023

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Cerevance

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                            AIChE Annual Meeting
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                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Gates Frontier

                            Deal Size : $116.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Cerevance Expands Series B Financing with Additional $51 Million

                            Details : The financing will support upcoming clinical trials focused on Parkinson’s disease, Amyotrophic Lateral Sclerosis, and schizophrenia including CVN424, a first-in-class, oral, brain penetrant, non-dopaminergic, GPR6 inverse agonist in Phase 2 trial for ...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 13, 2023

                            Lead Product(s) : Solengepras

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Gates Frontier

                            Deal Size : $116.0 million

                            Deal Type : Series B Financing

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