

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Cemsidomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : RA Capital Management
Deal Size : $125.0 million
Deal Type : Public Offering
C4 Therapeutics Sets $125M Underwritten Offering Price
Details : The proceeds from the offering will be used to fund the clinical development of Cemsidomide, targeting Cereblon for Multiple Myeloma treatment.
Product Name : CFT7455
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 16, 2025
Lead Product(s) : Cemsidomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : RA Capital Management
Deal Size : $125.0 million
Deal Type : Public Offering

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Lead Product(s) : Cemsidomide,Elranatamab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Collaboration
C4 Therapeutics Announces Clinical Trial Collaboration and Supply Agreement with Pfizer
Details : Pfizer will supply Elrexfio (elranatamab), a B-cell maturation antigen CD3 targeted bispecific antibody (BCMAxCD3 bispecific), to C4T for its CFT7455 (cemsidomide) upcoming Phase 1b trial.
Product Name : CFT7455
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 01, 2025
Lead Product(s) : Cemsidomide,Elranatamab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CFT7455 is an orally bioavailable MonoDAC degrader designed to be highly potent and selective against its intended targets of IKZF1 and IKZF3 and overcome shortcomings of currently approved therapies to treat multiple myeloma (MM) and non-Hodgkin’s lym...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 12, 2023
Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Single agent CFT7455 induces deep and durable degradation of IKZF1/3 and meaningful decreases in serum-free light chain at doses lower than expected based on pre-clinical studies.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 08, 2022
Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CFT7455 is an orally bioavailable MonoDAC™ (Monofunctional Degradation Activating Compound) designed to bind with high affinity to the E3 ligase adapter protein, cereblon, to target and degrade IKZF1/3 for the treatment of multiple myeloma and lymphoma...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 08, 2022
Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CFT7455 shows potent antiproliferative activity across a panel of NHL cell lines with MYC, BCL2, BCL6 translocations or rearrangements. This includes invitro models of cutaneous T-cell lymphoma, anaplastic large cell lymphoma, mantle cell lymphoma & high...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 21, 2021
Lead Product(s) : Cemsidomide,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Cemsidomide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cemsidomide is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Multiple Myeloma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 16, 2021
Lead Product(s) : Cemsidomide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
