[{"orgOrder":0,"company":"Lupin Ltd","sponsor":"Unitaid","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"INDIA","productType":"Antibiotic","year":"2022","type":"Agreement","leadProduct":"Rifapentine","moa":"||Bacterial DNA-directed RNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Lupin Ltd","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Lupin Ltd \/ Unitaid","highestDevelopmentStatusID":"15","companyTruncated":"Lupin Ltd \/ Unitaid"},{"orgOrder":0,"company":"Pharma 2100","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Isoniazid","moa":"Enoyl-[acyl-carrier-protein] reductase","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Pharma 2100","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Pharma 2100 \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Pharma 2100 \/ Inapplicable"},{"orgOrder":0,"company":"University of Massachusetts, Worcester","sponsor":"National Institute of Allergy and Infectious Diseases | Aurum Institute | A*STAR | University of Cape Town | Wits Health Consortium","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Isoniazid","moa":"Enoyl-[acyl-carrier-protein] reductase","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"University of Massachusetts, Worcester","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Pill","sponsorNew":"University of Massachusetts, Worcester \/ National Institute of Allergy and Infectious Diseases | Aurum Institute | A*STAR | University of Cape Town | Wits Health Consortium","highestDevelopmentStatusID":"8","companyTruncated":"University of Massachusetts, Worcester \/ National Institute of Allergy and Infectious Diseases | Aurum Institute | A*STAR | University of Cape Town | Wits Health Consortium"},{"orgOrder":0,"company":"National Institute of Allergy and Infectious Diseases","sponsor":"TB Alliance","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Isoniazid","moa":"Enoyl-[acyl-carrier-protein] reductase","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"National Institute of Allergy and Infectious Diseases","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"National Institute of Allergy and Infectious Diseases \/ TB Alliance","highestDevelopmentStatusID":"8","companyTruncated":"National Institute of Allergy and Infectious Diseases \/ TB Alliance"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI Korea
                          Not Confirmed
                          CPhI Korea
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 05, 2024

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : TB Alliance

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          CPhI Korea
                          Not Confirmed
                          CPhI Korea
                          Not Confirmed

                          Details : Through this agreement, Lupin will introduce two new formulations, a fixed-dose combination of Rifapentine + Isoniazid and Rifapentine 300 mg standalone tablets, at an affordable price for the treatment of tuberculosis.

                          Product Name : Rifapentine/Isoniazid-Generic

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          July 10, 2022

                          Lead Product(s) : Rifapentine,Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Unitaid

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          University of Massachusetts, Worcester

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          University of Massachusetts, Worcester

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : National Institute of Allergy and Infectious Diseases | Aurum Institute | A*STAR | University of Cape Town | Wits Health Consortium

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 18, 2021

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : National Institute of Allergy and Infectious Diseases | Aurum Institute | A*STAR | University of Cape Town | Wits Health Consortium

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma 2100

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Pharma 2100

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 17, 2021

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Beijing Chest Hospital

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Beijing Chest Hospital

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase IV

                          Sponsor : Hubei Provincial Center for Disease Control and Prevention | Centre for Tuberculosis Control of Guangdong Province | Hunan Institute For Tuberculosis Control | Anhui Chest Hospital | Guangxi Zhuang Autonomous Region Center for Disease Prevention and Contr

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 15, 2016

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Hubei Provincial Center for Disease Control and Prevention | Centre for Tuberculosis Control of Guangdong Province | Hunan Institute For Tuberculosis Control | Anhui Chest Hospital | Guangxi Zhuang Autonomous Region Center for Disease Prevention and Contr

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          CPhI Korea
                          Not Confirmed
                          CPhI Korea
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 10, 2015

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : National Defense Medical Center, Taiwan | NRPB, Taiwan

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Shanghai Pulmonary Hospital

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Shanghai Pulmonary Hospital

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase IV

                          Sponsor : Shanghai Center for Disease Control and Prevention | Jiangsu Province Centers for Disease Control and Prevention | Zhejiang University | Centers for Disease Control and Prevention

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 06, 2015

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Shanghai Center for Disease Control and Prevention | Jiangsu Province Centers for Disease Control and Prevention | Zhejiang University | Centers for Disease Control and Prevention

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Bridge BioResearch

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Bridge BioResearch

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 27, 2011

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Hospital Universitari de Bellvitge

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Hospital Universitari de Bellvitge

                          Country arrow
                          CPhI Korea
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 19, 2010

                          Lead Product(s) : Isoniazid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Cellestis

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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