Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Catabasis Pharmaceuticals To Present At Ladenburg Thalmann 2021 Healthcare Conference
Details : The lead program, QLS-215, is a monoclonal antibody inhibitor of plasma kallikrein in preclinical development for the treatment of hereditary angioedema.
Product Name : QLS-215
Product Type : Antibody
Upfront Cash : Inapplicable
July 07, 2021
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $110.0 million
Deal Type : Private Placement
Catabasis Pharmaceuticals Announces Acquisition of Quellis Biosciences Inc.
Details : Through the acquisition, Catabasis strengthens its pipeline by including QLS-215, a Potential Best-in-Class Monoclonal Antibody Inhibitor of Plasma Kallikrein in Preclinical Development for the Treatment of Hereditary Angioedema.
Product Name : QLS-215
Product Type : Antibody
Upfront Cash : Undisclosed
January 29, 2021
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $110.0 million
Deal Type : Private Placement
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The posters provide an overview of the baseline status of patients involved in PolarisDMD Ph 3 trial, findings from the MoveDMD Ph 2 trial and effect of oral edasalonexent in both the clinical trials.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase 3 PolarisDMD trial of edasalonexent in Duchenne muscular dystrophy (DMD) did not meet the primary endpoint, which was a change from baseline in the North Star Ambulatory Assessment (NSAA) over one year of edasalonexent compared to placebo.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 26, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The posters include new preclinical research findings supporting potential positive effects on cardiac function and preservation of bone health with edasalonexent in mouse models of DMD.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 28, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Duchenne Uk
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership is to evaluate Edasalonexent a novel NF-kB inhibitor, in a Phase 2 Non-Ambulatory Duchenne Muscular Dystrophy Trial.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 01, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Duchenne Uk
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Catabasis Pharmaceuticals to Present at Parent Project Muscular Dystrophy Virtual Annual Conference
Details : Catabasis Pharmaceuticals will present information on the edasalonexent program in Phase 3 development for the treatment of Duchenne muscular dystrophy (DMD) at the Parent Project Muscular Dystrophy (PPMD) Virtual Annual Conference.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 15, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Catabasis Pharmaceuticals to Present at 2020 Muscular Dystrophy Association Virtual Poster Session
Details : Catabasis Pharmaceuticals to present information on the edasalonexent program in Phase 3 development for the treatment of Duchenne muscular dystrophy (DMD).
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 17, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CAT-5571
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreements aims at assessing CAT-5571 as a potential oral therapy to promote autophagy and clear persistent lung infections in patients with both drug-sensitive and drug-resistant tuberculosis (TB).
Product Name : CAT-5571
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 08, 2020
Lead Product(s) : CAT-5571
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Edasalonexent, an NF-kB inhibitor in Phase 3 development for the treatment of Duchenne muscular dystrophy, is the company's lead program.
Product Name : CAT-1004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 20, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable