
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Onvansertib,Bevacizumab,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cardiff Completes Enrollment in Onvansertib Trial for Metastatic CRC
Details : PCM-075 (onvansertib) is a PLK-1 inhibitor, which is being evaluated in combination with Folfiri & Bevacizumab for the treatment of second-line RAS-mutated metastatic colorectal cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 15, 2025
Lead Product(s) : Onvansertib,Bevacizumab,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Irinotecan Hydrochloride,Calcium Folinate,Fluorouracil,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : University of Kansas Medical Center
Deal Size : Inapplicable
Deal Type : Inapplicable
Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer
Details : Onvansertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Pancreatic Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 17, 2024
Lead Product(s) : Onvansertib,Irinotecan Hydrochloride,Calcium Folinate,Fluorouracil,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : University of Kansas Medical Center
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cardiff Oncology Announces Positive Initial Data from RAS-mutated mCRC Clinical Trial
Details : PCM-075 (onvansertib) is a PLK-1 inhibitor, which is being evaluated in combination with Folfiri & Bevacizumab for the treatment of second-line RAS-mutated metastatic colorectal cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : TD Cowen
Deal Size : $40.0 million
Deal Type : Public Offering
Cardiff Oncology Prices Oversubscribed $40 Million Underwritten Registered Direct Offering
Details : The company intends to use the net proceeds from this offering to fund clinical development of PCM-075 (onvansertib) for the first-line RAS-mutated metastatic colorectal cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 10, 2024
Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : TD Cowen
Deal Size : $40.0 million
Deal Type : Public Offering

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Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cardiff Doses First Patient in First-Line RAS-Mutated Metastatic Colorectal Cancer Trial
Details : PCM-075 (onvansertib) is a PLK-1 inhibitor, which is being evaluated in combination with Folfiri & Bevacizumab for the treatment of second-line RAS-mutated metastatic colorectal cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 29, 2024
Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cardiff Provides Update on Phase 2 ONSEMBLE Trial in Patients with RAS-Mutated mCRC
Details : PCM-075 (onvansertib) is a PLK-1 inhibitor, which is being evaluated in combination with Folfiri & Bevacizumab for the treatment of second-line RAS-mutated metastatic colorectal cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 29, 2024
Lead Product(s) : Onvansertib,Bevacizumab,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Calcium Folinate,Fluorouracil,Irinotecan Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Pfizer Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Onvansertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 30, 2023
Lead Product(s) : Onvansertib,Calcium Folinate,Fluorouracil,Irinotecan Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Pfizer Inc
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Bevacizumab,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Onvansertib, a PLK1 inhibitor being evaluated in combination with standard-of-care (SoC) therapeutics in clinical programs targeting indications such as RAS-mutated metastatic colorectal cancer (mCRC) and metastatic pancreatic ductal adenocarcinoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 07, 2023
Lead Product(s) : Onvansertib,Bevacizumab,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Irinotecan HCl Trihydrate,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCM-075 (onvansertib) is a PLK1 inhibitor being evaluated in combination with standard-of-care (SoC) therapeutics in clinical programs targeting indications such as KRAS/NRAS-mutated cancers.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 28, 2023
Lead Product(s) : Onvansertib,Irinotecan HCl Trihydrate,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Onvansertib,Calcium Folinate,Fluorouracil,Irinotecan Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Onvansertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 25, 2022
Lead Product(s) : Onvansertib,Calcium Folinate,Fluorouracil,Irinotecan Hydrochloride,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
