Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : KJ-103
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : KisoJi Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Cancer Research UK & KisoJi Advance TROP2 Antibody into Clinic
Details : The collaboration aims to bring KisoJi's lead asset, KJ-103, into a first-in-human clinical trial. KJ-103 is a naked anti-TROP2 antibody using its proprietary antibody technology.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
October 24, 2024
Lead Product(s) : KJ-103
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : KisoJi Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : UCB6114,Trifluridine,Tipiracil HCl
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : UCB Pharma S.A
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration focuses on the development of two antibody candidates, UCB6114 and UCB4594 by bringing together the oncology-focused translational research and clinical development capabilities of Cancer Research UK, and UCB’s renowned antibody disco...
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Undisclosed
September 03, 2023
Lead Product(s) : UCB6114,Trifluridine,Tipiracil HCl
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : UCB Pharma S.A
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AST-VAC2
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Lineage Cell Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AST-VAC2 is an allogeneic, or non-patient specific, cancer vaccine candidate designed to stimulate patient immune responses to telomerase which is commonly expressed in cancerous cells but not in normal adult cells.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
July 24, 2023
Lead Product(s) : AST-VAC2
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Lineage Cell Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HTL0039732
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Sosei Group Corporation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the Clinical Trial and Licence Agreement (CTLA), Cancer Research UK’s Centre for Drug Development will sponsor, design and execute a Phase I/IIa clinical trial of HTL00397322, a novel selective EP4 antagonist.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 22, 2022
Lead Product(s) : HTL0039732
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Sosei Group Corporation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : BI-1206,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : BioInvent
Deal Size : Undisclosed
Deal Type : Collaboration
BioInvent Streamlines Agreement on Anti-Fcγ Rll B Antibody, BI-1206, Ahead of Phase I/II Data
Details : BioInvent is conducting a Phase I/II trial of BI-1206 in combination with rituximab to treat NHL. CRUK decided to end the trial being conducted in the UK after the single-agent part of the study. Both parties have agreed to restructure their agreement co...
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Undisclosed
November 01, 2021
Lead Product(s) : BI-1206,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : BioInvent
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : ALETA-001
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Aleta Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Cancer Research UK’s Centre for Drug Development will fund, sponsor and conduct the first-in-human Phase 1/2a clinical trial of ALETA-001, which will be led by Dr Amit Patel’s Cellular and CAR-T therapies team at The Christie NHS Foundation Trust in ...
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 23, 2021
Lead Product(s) : ALETA-001
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Aleta Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : TT-702
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Teon Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Cancer Research UK and Teon Therapeutics Advance New First-in-Class Cancer Drug Into Clinical Trial
Details : The partnership focuses on Teon’s potentially first-in-class small molecule adenosine A2B receptor antagonist TT-702, for the treatment of multiplecancers including prostate and triple-negative breast.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 03, 2021
Lead Product(s) : TT-702
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Teon Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Ideaya Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
IDEAYA Biosciences and Cancer Research UK Announce Expanded Research Collaboration
Details : The expanded research collaboration will evaluate IDEAYA's PARG inhibitors in vitro in multiple ovarian cancer cell lines and in vivo in ovarian cancer xenograft models.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 03, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Ideaya Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AST-VAC2
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Lineage Cell Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VAC2 demonstrated remarkably potent induction of immune responses in all patients dosed to date, with high levels of peripheral antigen-specific immunogenicity observed at multiple time points and confirmed by multimer staining.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
October 13, 2020
Lead Product(s) : AST-VAC2
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Lineage Cell Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed,Ipilimumab,Nivolumab
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : Microbiotica
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration is based on clinical studies conducted by CUH that evaluate immune checkpoint inhibitor drug response in cancer patients, combined with Microbiotica’s unrivalled microbiome profiling and analysis capability.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 06, 2020
Lead Product(s) : Undisclosed,Ipilimumab,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : Microbiotica
Deal Size : Undisclosed
Deal Type : Collaboration