Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Bio Reports Deepening Responses with Rese-cel at Scientific Meetings
Details : CABA-201 (resecabtagene autoleuce) is a fully human CD19 CAR-T cell therapy containing a 4-1BB co-stimulatory domain. It is being evaluated for systemic lupus erythematosus.
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 18, 2025
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Bio to Present Updated Rese-cel Clinical Data at February Meetings
Details : Rese-cel (resecabtagene autoleuce) is a fully human CD19 CAR-T cell therapy containing a 4-1BB co-stimulatory domain. It is being evaluated for systemic lupus erythematosus.
Product Name : Rese-cel
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 11, 2025
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Gets FDA Fast Track for CABA-201 in Dermatomyositis and Systemic Sclerosis
Details : CABA-201, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. It is being evaluated in preclinical studies for the treatment of dermatomyositis and systemic sclerosis.
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 01, 2024
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Bio: Positive Data from Phase 1/2 RESET-Myositis and RESET-SLE Trials
Details : CABA-201 is a 4-1BB-containing fully human CD19-CAR T cell investigational therapy, which is being evaluated for the treatment of idiopathic inflammatory myopathies (IIM, or myositis).
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 14, 2024
Lead Product(s) : Resecabtagene Autoleucel,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Announces FDA Grants Orphan Drug Designation to CABA-201 for Systemic Sclerosis
Details : CABA-201 is a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. It is being evaluated in preclinical studies for the treatment of patients with systemic sclerosis.
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
March 20, 2024
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Musculoskeletal
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Receives FDA Orphan Designation for CABA-201 in Myositis
Details : CABA-201 is a 4-1BB-containing fully human CD19-CAR T cell investigational therapy, which is being evaluated in phase 1/2 clinical trials for idiopathic inflammatory myopathies (IIM, or myositis).
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 02, 2024
Lead Product(s) : Resecabtagene Autoleucel,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CABA-201, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy, has been allowed to proceed by the U.S. Food and Drug Administration (FDA) for a Phase 1/2 study in patients with generalized myasthenia gravis (gMG).
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 11, 2023
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Details : The net proceedings will be used for expanded clinical development of CABA-201 in multiple indications, to advance manufacturing capabilities in preparation for late-stage trials and commercial readiness for CABA-201, and the ongoing development for its ...
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 22, 2023
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : TD Cowen
Deal Size : $87.0 million
Deal Type : Public Offering
Cabaletta Bio Announces Pricing of Public Offering of Common Stock
Details : Cabaletta will use the net proceeds for expanded clinical development of CABA-201 in multiple indications, to advance manufacturing capabilities in preparation for late-stage trials and commercial readiness for CABA-201, and the ongoing development for i...
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 17, 2023
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : TD Cowen
Deal Size : $87.0 million
Deal Type : Public Offering
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cabaletta Bio Receives FDA Clearance of IND Application for CABA-201 for Treatment of Myositis
Details : CABA-201 is a 4-1BB-containing fully human CD19-CAR T cell investigational therapy, has been cleared by the U.S. Food and Drug Administration for a Phase 1/2 study in patients with active idiopathic inflammatory myopathy (IIM, or myositis).
Product Name : CABA-201
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
May 16, 2023
Lead Product(s) : Resecabtagene Autoleucel
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable