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[{"orgOrder":0,"company":"BioCardia","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Biocardia Announces Positive DSMB Recommendation To Continue Phase 3 Pivotal CardiAMP Heart Failure Study As Planned","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"Undisclosed","date":"March 2020","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III"},{"orgOrder":0,"company":"BioCardia","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"BioCardia Announces Preclinical Results Supporting Investigational New Drug Application for Anti-Inflammatory Cell Therapy in Heart Failure","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Preclinical","country":"U.S.A","productType":"Cell and Gene 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            CardiAMP cell therapy is the first comprehensive therapeutic treatment utilizing a patient's own cells for the treatment. It is being evaluated in phase 3 clinical trials for the treatment of ischemic etiology heart failure of reduced ejection fraction.

            Lead Product(s): BCDA-01

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: CardiAMP

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 08, 2024

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            The Company intends to use the net proceeds for advancing the Company’s investigational biotherapeutic candidates, including BCDA-01 (CardiAMP cell therapy) for the treatment of heart failure.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

            Deal Size: $1.3 million Upfront Cash: Undisclosed

            Deal Type: Public Offering November 16, 2023

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            BCDA-01 (CardiAMP Cell Therapy) uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 14, 2023

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            BCDA-01 (CardiAMP Cell Therapy) uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 11, 2023

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            BCDA-01 (CardiAMP Cell Therapy) uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 05, 2023

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            BCDA-01 (CardiAMP Cell Therapy) uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 24, 2023

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            BCDA-01 (cardiAMP cell therapy), designated as an FDA Breakthrough therapy which uses a patient’s own bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially used for ischemic heart failure with reduced ejection fraction.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 05, 2023

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            Details:

            BCDA-01 (cardiAMP Cell Therapy) designated as an FDA Breakthrough Device uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially used for ischemic heart failure with reduced ejection fraction.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: BCDA-01

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 20, 2023

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            CardiAMP Cell Therapy designated as an FDA Breakthrough Device uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response.

            Lead Product(s): CardiAMP Cell Therapy

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

            Highest Development Status: Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 23, 2023

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            USPTO has granted patent to NK1R+ MSCs which utilizes younger, universal donor mesenchymal stem cells and may be appropriate for patients who are not optimal candidates for the CardiAMP therapy. It is also being investigated in pulmonary acute respiratory distress.

            Lead Product(s): Mesenchymal Stem Cell

            Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 09, 2023

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