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    [{"orgOrder":0,"company":"Bexion Pharmaceuticals","sponsor":"Icon Plc | CTI Clinical Trial and Consulting","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2022","type":"Inapplicable","leadProduct":"BXQ-350","moa":"S1P receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Bexion Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bexion Pharmaceuticals \/ Icon Plc | CTI Clinical Trial and Consulting","highestDevelopmentStatusID":"7","companyTruncated":"Bexion Pharmaceuticals \/ Icon Plc | CTI Clinical Trial and Consulting"},{"orgOrder":0,"company":"Bexion Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Saposin C","moa":"S1P 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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Saposin C-dioleoylphosphatidylserine","moa":"Spingomyelinase catalysis","graph1":"Oncology","graph2":"Phase I","graph3":"Bexion Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Bexion Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Bexion Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Bexion Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Saposin C","moa":"S1P receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Bexion Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph 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                            01

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bexion Completes Enrollment for Phase 1b/2 ASIST Study in mCRC Patients

                            Details : BXQ-350, a first-in-class biologic containing the multifunctional sphingolipid activator protein, for the treatment of metastatic colorectal cancer.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            November 18, 2024

                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Michael J. Fox Foundation for Parkinson’s Research

                            Deal Size : $1.4 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Bexion Receives MJFF Grant for BXQ-350 Advancement

                            Details : The grant will fund the preclinical development of BXQ-350, a first-in-class biologic containing the multifunctional sphingolipid activator protein, for the treatment of Parkinson's disease (PD).

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            November 14, 2024

                            Lead Product(s) : Saposin C

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Michael J. Fox Foundation for Parkinson’s Research

                            Deal Size : $1.4 million

                            Deal Type : Funding

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                            03

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bexion Pharmaceuticals, Inc. Announces Publication of Pediatric Phase 1 (KOURAGE) Results

                            Details : BXQ-350 increases ceramides and decreases sphingosine-1-phosphate (S1P) to selectively target tumor cells and only tumor cells. It is being developed for relapsed solid tumors.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 23, 2023

                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Bexion Pharmaceuticals

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                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Icon Plc | CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            April 12, 2022

                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Icon Plc | CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Bexion Pharmaceuticals

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                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BXQ-350 Pharmacokinetic/Pharmacodynamic Study in Cancer Patients

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 22, 2022

                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C,Dioleoyl Phosphatidylserine

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bexion Pharmaceuticals Receives Study May Proceed Letter from FDA for a Phase 1b/2 Clinical Trial of BXQ-350 i...

                            Details : BXQ-350 is a novel anti-neoplastic therapeutic agent configured from two components: Saposin C (SapC), an expressed (human) lysosomal protein, and the phospholipid dioleoylphosphatidyl-serine (DOPS), a cell membrane phospholipid used for solid tumors and...

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            September 29, 2021

                            Lead Product(s) : Saposin C,Dioleoyl Phosphatidylserine

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Bexion Pharmaceuticals

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                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 25, 2021

                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C-dioleoylphosphatidylserine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bexion Pharmaceuticals Receives Orphan Drug Designation for BXQ-350 for Malignant Glioma from FDA

                            Details : U.S FDA has granted Bexion Pharmaceuticals an Orphan Drug Designation for its proprietary drug, BXQ-350, for the treatment of malignant glioma, including diffuse intrinsic pontine glioma (DIPG).

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            July 05, 2020

                            Lead Product(s) : Saposin C-dioleoylphosphatidylserine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Bexion Pharmaceuticals

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                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Continued Treatment for Participants Enrolled in Studies of BXQ-350

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            May 27, 2020

                            Lead Product(s) : BXQ-350

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : CTI Clinical Trial and Consulting

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Bexion Pharmaceuticals

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                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bexion Pharmaceuticals Presenting BXQ-350 Data at ASCO 2020

                            Details : The presentations will focus on BXQ-350, Bexion's first-in-class agent composed of the multifunctional, lysosomal activator protein Saposin C and phosphatidylserine, for refractory solid tumors and high-grade gliomas.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            May 13, 2020

                            Lead Product(s) : Saposin C

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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