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    [{"orgOrder":0,"company":"Bellicum Pharmaceuticals","sponsor":"The University of Texas MD Anderson Cancer Center","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Licensing Agreement","leadProduct":"Rimiducid","moa":"||Undisclosed","graph1":"Oncology","graph2":"Undisclosed","graph3":"Bellicum Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Bellicum Pharmaceuticals \/ The University of Texas MD Anderson Cancer Center","highestDevelopmentStatusID":"1","companyTruncated":"Bellicum Pharmaceuticals \/ The University of Texas MD Anderson Cancer Center"},{"orgOrder":0,"company":"Bellicum Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene 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Securities"},{"orgOrder":0,"company":"Bellicum Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Inapplicable","leadProduct":"BPX-603","moa":"||HER2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Bellicum Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Bellicum Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Bellicum Pharmaceuticals \/ Inapplicable"}]

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                            01

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Discontinues Phase 1/2 Trials and Initiates Evaluation of Strategic Alternatives

                            Details : BPX-601 incorporates high-performance GoCAR-T™ technology designed to target and treat solid tumors expressing prostate stem cell antigen (PSCA). It is being discontinued following the company’s assessment of BPX-601 risk/benefit profile in combinati...

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 14, 2023

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Pharmaceuticals to Present Early Phase 1 Results for BPX-601 in Prostate Cancer at ASCO 2023 Genitour...

                            Details : BPX-601 is our first clinical candidate incorporating our high-performance GoCAR-Tâ„¢ technology designed to target and treat solid tumors expressing prostate stem cell antigen (PSCA).

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 19, 2023

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : MTS Securities

                            Deal Size : $35.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Bellicum Announces Positive Interim Data from Phase 1/2 GoCAR-T® Studies, Secures $35 Million Private Placeme...

                            Details : Proceeds from the financing will be used to support ongoing clinical development of BPX-601 and BPX-603, are designed to be more efficacious CAR-T cell products capable of overriding key immune inhibitory mechanisms.

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 12, 2021

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : MTS Securities

                            Deal Size : $35.0 million

                            Deal Type : Private Placement

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                            04

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : Undisclosed,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : The University of Texas MD Anderson Cancer Center

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Bellicum and MD Anderson Announce Additional License Agreement for Use of CaspaCIDe® Safety Switch

                            Details : Under this agreement, MD Anderson will have the option to incorporate CaspaCIDe into certain cellular therapy programs. The CaspaCIDe switch consists of the CID-binding domain coupled to the signaling domain of caspase-9, an enzyme that is part of the ap...

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $5.0 million

                            January 09, 2021

                            Lead Product(s) : Undisclosed,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : The University of Texas MD Anderson Cancer Center

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            05

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Announces Interim BPX-601 Data and Corporate Restructuring

                            Details : Findings from the first four patients treated with BPX-601 followed by repeat rimiducid dosing showed evidence of rimiducid-mediated CAR-T cell activation. Clinically meaningful efficacy as measured by RECIST criteria was not observed.

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 29, 2020

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-603,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Enrolls First Patient in Phase 1/2 Clinical Trial for BPX-603

                            Details : BPX-603 is Bellicum’s first dual switch GoCAR-T product candidate that incorporates the company’s iMC activation and CaspaCIDe safety switch technologies. Phase 1/2 trial will investigate the safety, tolerability, and clinical activity of BPX-603, ad...

                            Product Name : BPX-603

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 12, 2020

                            Lead Product(s) : BPX-603,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Reports Clinical Hold Placed on BPX-601 Phase 1/2 Clinical Trial

                            Details : The FDA is taking this action due to the death of a pancreatic cancer patient in the trial reported to the agency by the company. The clinical investigator and Bellicum classified the patient death as unrelated to BPX-601 and rimiducid.

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            July 12, 2020

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-603

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Receives FDA IND Clearance to Initiate a Phase 1/2 Clinical Trial for BPX-603, a Dual-Switch GoCAR-TÂ...

                            Details : BPX-603 is the company’s first dual-switch GoCAR-T® product candidate, which incorporates both the company’s iMC activation and CaspaCIDe® safety switch technologies.

                            Product Name : BPX-603

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            June 15, 2020

                            Lead Product(s) : BPX-603

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MD Anderson Research Freeze Stops Production of Bellicum Drugs

                            Details : Bellicum is currently involved in 12 active studies, including a phase 1/2 trial of BPX-601 CAR-T cells in advanced solid tumors that express high levels of PSCA.

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 17, 2020

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Bellicum Pharmaceuticals

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                            AMWC Asia-TDAC
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                            Bellicum Pharmaceuticals

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                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bellicum Presents New Translational Data for BPX-601 at ASCO GI Cancers Symposium

                            Details : A cohort treated with BPX-601 and a single dose of rimiducid showed immunomodulation in both the periphery and tumor microenvironment.

                            Product Name : BPX-601

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 24, 2020

                            Lead Product(s) : BPX-601,Rimiducid

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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