Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AVZO-1418
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Avenzo gets IND Clearance for AVZO-1418 EGFR/HER3 Bispecific ADC
Details : AVZO-1418, a potential best-in-class, novel EGFR/HER3 bispecific antibody-drug conjugate. It is being evaluated for the treatment of advanced solid tumors.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
May 22, 2025
Lead Product(s) : AVZO-1418
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AVZO-023
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Allorion Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Avenzo gets FDA IND Clearance for AVZO-023 CDK4 Inhibitor for Cancer
Details : Under the licensing agreement, Avenzo has exercised its exclusive option for global (excluding Greater China) development, manufacturing, and commercialization rights for AVZO-023.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 21, 2025
Lead Product(s) : AVZO-023
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Allorion Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : DB-1418
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Duality Biologics
Deal Size : $1,200.0 million
Deal Type : Licensing Agreement
Avenzo, DualityBio Sign License for EGFR/HER3 Antibody-Drug Conjugate
Details : Under the licensing agreement, Venzo will develop, manufacture and commercialize AVZO-1418 (DB-1418), a potential best-in-class bispecific ADC for treating neoplasms.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : $50.0 million
January 07, 2025
Lead Product(s) : DB-1418
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Duality Biologics
Deal Size : $1,200.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : VelaVigo
Deal Size : Undisclosed
Deal Type : Licensing Agreement
VelaVigo Licenses Nectin4/TROP2 Bispecific Antibody-Drug Conjugate from Avenzo
Details : Avenzo gains an exclusive option to an exclusive license to develop, manufacture and commercialize a potential first-in-class Nectin4/TROP2 bispecific ADC globally (excluding Greater China).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 18, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : VelaVigo
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : AVZO-021,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Allorion Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Avenzo Announces Global License of AVZO-021 (ARTS-021) from Allorion Therapeutics
Details : Under the agreement, Avenzo will develop and commercialize AVZO-021 (formerly ARTS-021), a potentially best-in-class cyclin-dependent kinase 2 selective inhibitor globally, excluding Greater China.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 01, 2024
Lead Product(s) : AVZO-021,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Allorion Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : AVZO-021,Fulvestrant,Letrozole
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : New Enterprise Associates
Deal Size : $150.0 million
Deal Type : Series A Financing
Avenzo Therapeutics Announces $150M Oversubscribed Financing for Oncology
Details : Proceeds will advance Avenzo’s ARTS-021, a selective CDK2 inhibitor in a Phase 1 study for HR+/HER2- metastatic breast cancer and other advanced solid tumors.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 26, 2024
Lead Product(s) : AVZO-021,Fulvestrant,Letrozole
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : New Enterprise Associates
Deal Size : $150.0 million
Deal Type : Series A Financing
Lead Product(s) : AVZO-021,Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Gilead Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Avenzo Partners with Gilead For Breast Cancer Study with AVZO-021
Details : The collaboration aims to evaluate AVZO-021, a best-in-class CDK2 inhibitor, in combination with Gilead’s Trodelvy (sacituzumab govitecan), for patients with HR-positive, HER2-negative breast cancer.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 09, 2024
Lead Product(s) : AVZO-021,Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Gilead Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AVZO-021
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of AVZO-021 in Patients With Advanced Solid Tumors
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 19, 2023
Lead Product(s) : AVZO-021
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable