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    [{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"AVZO-021","moa":"CDK2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Allorion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Licensing Agreement","leadProduct":"AVZO-021","moa":"||CDK2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Associates","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Series A Financing","leadProduct":"AVZO-021","moa":"||CDK2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0.14999999999999999,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.14999999999999999,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ New Enterprise Associates","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ New Enterprise Associates"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Allorion Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Licensing Agreement","leadProduct":"AVZO-023","moa":"CDK4","graph1":"Oncology","graph2":"IND Enabling","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Avenzo Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Avenzo Therapeutics \/ Avenzo Therapeutics"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Duality Biologics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody-drug Conjugate","year":"2025","type":"Licensing Agreement","leadProduct":"DB-1418","moa":"DNA topoisomerase I","graph1":"Oncology","graph2":"IND Enabling","graph3":"Avenzo Therapeutics","amount2":1.2,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":1.2,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Avenzo Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Avenzo Therapeutics \/ Avenzo Therapeutics"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"AVZO-1418","moa":"EGFR\/HER3","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"AVZO-1418","moa":"EGFR|HER3","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Fulvestrant","moa":"Estrogen receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"AVZO-103","moa":"Nectin4\/TROP2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"VelaVigo","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Undisclosed","year":"2024","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ Avenzo Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Avenzo Therapeutics \/ Avenzo Therapeutics"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"OrbiMed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Series B Financing","leadProduct":"AVZO-021","moa":"||CDK2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Avenzo Therapeutics \/ OrbiMed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ OrbiMed"},{"orgOrder":0,"company":"Avenzo Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"AVZO-103","moa":"Nectin4\/TROP2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Avenzo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Avenzo Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Avenzo Therapeutics \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals by Avenzo Therapeutics

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                            01

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
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                            Lead Product(s) : AVZO-103

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic...

                            Details : AVZO-103 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            September 26, 2025

                            Lead Product(s) : AVZO-103

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : AVZO-021,Palbociclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : OrbiMed

                            Deal Size : $60.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Avenzo Therapeutics Announces $60 Million Series B Financing

                            Details : Thew proceeds will be used to advance Avenzo’s portfolio of potential best-in-class oncology drug candidates, including AVZO-021, the company’s lead drug candidate.

                            Product Name : AVZO-021

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 22, 2025

                            Lead Product(s) : AVZO-021,Palbociclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : OrbiMed

                            Deal Size : $60.0 million

                            Deal Type : Series B Financing

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                            03

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
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                            Avenzo Therapeutics

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                            Bio-Europe Autumn
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                            Lead Product(s) : AVZO-103

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Avenzo Therapeutics Announces FDA Clearance of IND for AVZO-103

                            Details : AVZO-103, a potential best-in-class Nectin4/TROP2 bispecific antibody-drug conjugate. It is being evaluated for the treatment of advanced solid tumors.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            September 02, 2025

                            Lead Product(s) : AVZO-103

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : AVZO-1418

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AVZO-1418 Single/Combo Therapy Safety and Efficacy In Advanced Solid Tumors

                            Details : AVZO-1418 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 26, 2025

                            Lead Product(s) : AVZO-1418

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of AVZO-023 Alone or with AVZO-021/Endocrine Therapy in Advanced Solid Tumors

                            Details : Fulvestrant is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 31, 2025

                            Lead Product(s) : Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : AVZO-1418

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Avenzo gets IND Clearance for AVZO-1418 EGFR/HER3 Bispecific ADC

                            Details : AVZO-1418, a potential best-in-class, novel EGFR/HER3 bispecific antibody-drug conjugate. It is being evaluated for the treatment of advanced solid tumors.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            May 22, 2025

                            Lead Product(s) : AVZO-1418

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : AVZO-023

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Allorion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Avenzo gets FDA IND Clearance for AVZO-023 CDK4 Inhibitor for Cancer

                            Details : Under the licensing agreement, Avenzo has exercised its exclusive option for global (excluding Greater China) development, manufacturing, and commercialization rights for AVZO-023.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 21, 2025

                            Lead Product(s) : AVZO-023

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Allorion Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            08

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : DB-1418

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Duality Biologics

                            Deal Size : $1,200.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Avenzo, DualityBio Sign License for EGFR/HER3 Antibody-Drug Conjugate

                            Details : Under the licensing agreement, Venzo will develop, manufacture and commercialize AVZO-1418 (DB-1418), a potential best-in-class bispecific ADC for treating neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : $50.0 million

                            January 07, 2025

                            Lead Product(s) : DB-1418

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Duality Biologics

                            Deal Size : $1,200.0 million

                            Deal Type : Licensing Agreement

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                            09

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : VelaVigo

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            VelaVigo Licenses Nectin4/TROP2 Bispecific Antibody-Drug Conjugate from Avenzo

                            Details : Avenzo gains an exclusive option to an exclusive license to develop, manufacture and commercialize a potential first-in-class Nectin4/TROP2 bispecific ADC globally (excluding Greater China).

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            November 18, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : VelaVigo

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            10

                            Avenzo Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Avenzo Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : AVZO-021,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Gilead Sciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Avenzo Partners with Gilead For Breast Cancer Study with AVZO-021

                            Details : The collaboration aims to evaluate AVZO-021, a best-in-class CDK2 inhibitor, in combination with Gilead’s Trodelvy (sacituzumab govitecan), for patients with HR-positive, HER2-negative breast cancer.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 03, 2024

                            Lead Product(s) : AVZO-021,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Gilead Sciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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