
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Enlaza Therapeutics
Deal Size : $61.0 million
Deal Type : Financing
Details : Enlaza is developing first-in-class covalent protein-based therapeutics to transform the treatment of cancer and other serious diseases. The financing will be used to advance Enlaza’s proprietary War-Lock platform and build a pipeline of covalent biolo...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 15, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Enlaza Therapeutics
Deal Size : $61.0 million
Deal Type : Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Janux Therapeutics
Deal Size : $100.0 million
Deal Type : Public Offering
Cancer Biotech Janux Therapeutics Files for $100 Million IPO
Details : The company’s TRACTr technology is engineered to overcome limitations of current immuno-oncology T-cell therapies, primarily dose-limiting toxicities, poor pharmacokinetic profiles, and limited efficacy.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 21, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Janux Therapeutics
Deal Size : $100.0 million
Deal Type : Public Offering

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Janux Therapeutics
Deal Size : $56.0 million
Deal Type : Series A Financing
Details : The financing will be used to advance the Company’s preclinical pipeline, including a TROP2-TRACTr and PSMA-TRACTr, with expected advancement of the Company’s first candidate into the clinic in the first half of next year.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 03, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Janux Therapeutics
Deal Size : $56.0 million
Deal Type : Series A Financing

Details : Avalon is expanding its AVA-001 clinical trial to recruit patients with relapsed/refractory Non-Hodgkin lymphoma (R/R-NHL).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 01, 2020

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Lead Product(s) : AVA-001,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Completed Phase I Clinical Study of 4-1BB Based Anti-CD19 CAR-T Therapy for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia; Achieved 90% Complete Remission (CR) Rate with Minimum Toxicity or Adverse Side Effects.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
July 13, 2020
Lead Product(s) : AVA-001,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AVA-001,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Nine out of ten patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) have achieved complete remission (CR rate of 90%) within one month after the initiation of AVA-001 CAR T-cell therapy treatment.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 29, 2020
Lead Product(s) : AVA-001,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : S-Layer COVID Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : University Of Natural Resources
Deal Size : Undisclosed
Deal Type : Partnership
Avalon GloboCare to Develop Intranasal and Oral Covid-19 Vaccine
Details : Avalon forms strategic partnership with the University of Natural Resources and Life Sciences (BOKU) in Vienna, Austria and the nanotechnology laboratory of Professor Uwe B. Sleytr on a novel S-layer SARS-CoV-2 (COVID-19) vaccine.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
June 25, 2020
Lead Product(s) : S-Layer COVID Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : University Of Natural Resources
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : AVA-Trap
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Avalon’s AVA-Trap™ therapeutic program is currently entering animal model testing followed by expedited clinical studies with the goal of providing an effective therapeutic option to combat COVID-19.
Product Name : AVA-Trap
Product Type : Protein
Upfront Cash : Inapplicable
April 20, 2020
Lead Product(s) : AVA-Trap
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
