Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Autobahn Therapeutics Starts Phase 2 Trial of ABX-002 for Bipolar Depression
Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of bipolar depression.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 08, 2025
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Autobahn Gains IND Clearance for ABX-002 in Bipolar Depression Treatment
Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of bipolar depression.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2024
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Autobahn Initiates AMPLIFY Phase 2 Trial of ABX-002 for Major Depressive Disorder
Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of major depressive disorder as an adjunctive treatment.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 16, 2024
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Arch Ventures
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Completes $100M Series C Financing to Advance Depression Therapies
Details : The proceeds will commence two Phase 2 trials for the company’s lead program, ABX-002, a potent and selective thyroid hormone beta receptor agonist for depression and other CNS disorders.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Arch Ventures
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Canaan Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Completes $100M Series C Financing to Advance Depression Therapies
Details : The proceeds from the financing will be used to commence mid-stage trials for the company’s lead program, ABX-002 (methyl amide prodrug), a potent and selective thyroid hormone beta receptor agonist.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Canaan Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Newpath Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Raises 100M in Series C For CNS Drug Pipeline
Details : The proceeds will be used to commence two Phase 2 trials for company’s ABX-002, a potent and selective thyroid hormone beta receptor agonist, for MDD and bipolar disorder depression.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Newpath Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ABX-002 is a novel, orally administered, potent, and selective thyroid hormone beta agonist, which is investigated for the treatment of major depressive disorder.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 09, 2023
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ABX-002 is an orally administered, potent, selective thyroid hormone beta (TRβ) agonist that is brain enhanced, demonstrates target engagement in brain regions associated with depression.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 18, 2023
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Administration of ABX-002 resulted in potent and on-target responses in preclinical models of AMN and support company's continued advancement of ABX-002 toward clinical evaluation for the treatment of people with this rare and very difficult disease.
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 17, 2021
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : Arch Ventures
Deal Size : $76.0 million
Deal Type : Series B Financing
Details : Proceeds will be used to advance Autobahn’s lead program candidate, ABX-002, a thyroid hormone receptor beta agonist therapy for the treatment of multiple sclerosis (MS) and adrenomyeloneuropathy (AMN).
Product Name : ABX-002
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 06, 2020
Lead Product(s) : Methyl Amide Prodrug
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : Arch Ventures
Deal Size : $76.0 million
Deal Type : Series B Financing