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    [{"orgOrder":0,"company":"Aurion Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2024","type":"Inapplicable","leadProduct":"AURN001","moa":"Rho-associated protein kinase","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Aurion Biotech","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aurion Biotech \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Aurion Biotech \/ Undisclosed"},{"orgOrder":0,"company":"Aurion Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2023","type":"Inapplicable","leadProduct":"AURN001","moa":"Rho-associated protein kinase","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Aurion 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Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2023","type":"Inapplicable","leadProduct":"Neltependocel","moa":"Rho-associated protein kinase","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Aurion Biotech","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injection","sponsorNew":"Aurion Biotech \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Aurion Biotech \/ Undisclosed"},{"orgOrder":0,"company":"Aurion Biotech","sponsor":"Alcon Inc","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2025","type":"Acquisition","leadProduct":"Neltependocel","moa":"Rho-associated protein kinase","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Aurion 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Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2024","type":"Inapplicable","leadProduct":"Neltependocel","moa":"||Rho-associated protein kinase","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Aurion Biotech","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aurion Biotech \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Aurion Biotech \/ Undisclosed"},{"orgOrder":0,"company":"Aurion Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"HCEC-1","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Aurion Biotech","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aurion Biotech \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Aurion Biotech \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals by Aurion Biotech

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                            01

                            Aurion Biotech

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Aurion Biotech

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                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Alcon Inc

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Alcon Acquires Aurion Biotech To Advance Corneal Cell Therapy

                            Details : Aurion will operate as a separate company with full support from Alcon to advance its clinical-stage allogeneic cell therapy asset, AURN001 for the treatment of Corneal Edema in adult.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            March 26, 2025

                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Alcon Inc

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Announces Positive Data From Phase 1/2 Trial Of AURN001

                            Details : AURN001 is a cell therapy product comprised of neltependocel. It is being evaluated in combination with Y27632 for the treatment of corneal edema secondary to corneal endothelial dysfunction.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            December 18, 2024

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : AURN001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Cryopreserved AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

                            Details : AURN001 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Corneal Edema.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            October 08, 2024

                            Lead Product(s) : AURN001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Launches Vyznova® in Japan for Bullous Keratopathy

                            Details : Vyznova is a combination cell therapy product (biologic/drug) comprised of neltependocel & Y-27632, being evaluated for the treatment of bullous keratopathy of the cornea.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            September 24, 2024

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion's AURN001 Gets Breakthrough and RMAT Designations

                            Details : AURN001 is a cell therapy product comprised of neltependocel. It is being evaluated in combination with Y27632 for the treatment of corneal edema secondary to corneal endothelial dysfunction.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            June 19, 2024

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Announces Completion of Enrollment in Phase 1 / 2 Clinical Trial

                            Details : AURN001 is a combination cell therapy product comprised of neltependocel & Y-27632 . It is being evaluated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            April 30, 2024

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Announces First Canadian Subject Dosed in Phase 1 / 2 Clinical Trial

                            Details : AURN001 is a combination cell therapy product comprised of neltependocel & Y-27632 . It is being evaluated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            March 28, 2024

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Announces First Subject Dosed in U.S. Phase 1 / 2 Clinical Trial

                            Details : AURN001 (CECs and Y-27632) is a combination cell therapy product and administered to the eye as a one-time, intracameral injection, which is investigated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            October 24, 2023

                            Lead Product(s) : Neltependocel,Y27632

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : AURN001

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-...

                            Details : AURN001 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Corneal Edema.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            September 18, 2023

                            Lead Product(s) : AURN001

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Aurion Biotech

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                            AIChE Annual Meeting
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                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Genetic Disease

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aurion Biotech Receives Approval from Japan’s PMDA for New Drug Application

                            Details : Vyznova is a human corneal endothelial cell therapy which involves taking healthy corneal cells from donor corneas and culturing them to produce off-the-shelf, fully differentiated CEC making it a potential treatment paradigm for corneal endothelial dise...

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            March 23, 2023

                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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