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            AURN001 is a combination cell therapy product (biologic/drug) comprised of neltependocel & Y-27632 . It is being evaluated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

            Lead Product(s): Neltependocel,Y27632

            Therapeutic Area: Ophthalmology Product Name: AURN001

            Highest Development Status: Phase I/ Phase II Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 30, 2024

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            Details:

            AURN001 is a combination cell therapy product (biologic/drug) comprised of neltependocel & Y-27632 . It is being evaluated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

            Lead Product(s): Neltependocel,Y27632

            Therapeutic Area: Ophthalmology Product Name: AURN001

            Highest Development Status: Phase I/ Phase II Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 28, 2024

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            AURN001 (CECs and Y-27632) is a combination cell therapy product and administered to the eye as a one-time, intracameral injection, which is investigated for the treatment of corneal edema secondary to corneal endothelial dysfunction.

            Lead Product(s): Neltependocel,Y27632

            Therapeutic Area: Ophthalmology Product Name: AURN001

            Highest Development Status: Phase I/ Phase II Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 24, 2023

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            Vyznova is a human corneal endothelial cell therapy which involves taking healthy corneal cells from donor corneas and culturing them to produce off-the-shelf, fully differentiated CEC making it a potential treatment paradigm for corneal endothelial disease.

            Lead Product(s): Human Corneal Endothelial Cell Therapy

            Therapeutic Area: Genetic Disease Product Name: Vyznova

            Highest Development Status: Approved Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 23, 2023

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