Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Astrocyte Gets FDA Clearance for AST-004 IND Application
Details : Astrocyte AST-004, an innovative small molecule therapy, which is an adenosine A3/A1 receptor agonist, is being evaluated in Phase I clinical trial studies with patients for Acute Ischemic Stroke.
Product Name : AST-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 03, 2024
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AST-004
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Alzheimers Drug Discovery Foundation
Deal Size : $6.0 million
Deal Type : Series B Financing
Details : The funding will accelerate the development of AST-004, a small molecule adenosine A3/A1 receptor agonist, aimed at treating acute brain injuries including stroke and traumatic brain injury (TBI), and further assess its potential in preclinical models of...
Product Name : AST-004
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 18, 2023
Lead Product(s) : AST-004
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Alzheimers Drug Discovery Foundation
Deal Size : $6.0 million
Deal Type : Series B Financing
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AST-004 is a small molecule adenosine A3/A1 receptor agonist, it is being investigated as an extended infusion for stroke and traumatic brain injuries.
Product Name : AST-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 04, 2023
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AST-004 was extremely well tolerated at all dose levels, and there have been no safety signals or significant adverse effects associated with AST-004.
Product Name : AST-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 14, 2022
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AST-004 has demonstrated a broad range of cerebroprotective efficacy when treating preclinical animal models, including preserving up to 45 percent more brain tissue in a non-human primate model of stroke, beyond that of reperfusion standard of care.
Product Name : AST-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 15, 2022
Lead Product(s) : AST-004
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable