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                          01

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : The data shows that ARU-1801 offers potential long-term improvement of the primary symptoms seen with SCD without the toxicities and resource utilization associated with fully myeloablative chemotherapies.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          October 06, 2022

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : Data demonstrate that ARU-1801 gene therapy may not only be able to reduce severe vaso-occlusive events but also reduce days in hospital for SCD patients, which could provide a clinically meaningful benefit for patients and help reduce health care costs.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          May 16, 2022

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : ARU-1801 is designed to address the limitations of current curative allogeneic transplant options, such as low donor availability, the risk of graft-versus-host disease and toxicity from myeloablative chemotherapy.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 19, 2022

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : In partnership with SCDAA, Aruvant is working to educate patients about gene therapy, while gaining critical insights from the patient community for its ARU-1801 SCD development program.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 10, 2020

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Sickle Cell Disease Association Of America

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : Preliminary clinical data from Aruvant's ongoing Phase 1/2 study that demonstrates ARU-1801, administered with only reduced intensity conditioning, can achieve durable reductions in disease burden.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          November 16, 2020

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : Data presented at ASH is from the MOMENTUM study, an open label Phase 1/2 clinical trial examining ARU-1801 as a one-time potentially curative gene therapy for individuals with sickle cell disease (SCD).

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 11, 2020

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Arvo
                          Not Confirmed
                          Arvo
                          Not Confirmed

                          Details : Aruvant's ARU-1801, received FDA Orphan Drug designation for its efficacy to deliver a highly potent gene payload with enhanced anti-sickling properties, for a Reduced Intensity Conditioning regimen.

                          Product Name : ARU-1801

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 22, 2020

                          Lead Product(s) : ARU-1801

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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