Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AB-101,Acimtamig,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $167.0 million
Deal Type : Public Offering
Artiva upsizes IPO to $167 million as NK cell therapy biotech heads to Nasdaq
Details : The net proceeds will be used to fund the clinical development of the company's lead product AlloNK (AB-101), which is being evaluated for the treatment of r/r Hodgkin Lymphoma.
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 18, 2024
Lead Product(s) : AB-101,Acimtamig,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $167.0 million
Deal Type : Public Offering
Lead Product(s) : AB-101,Cyclophosphamide,Rituximab
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Artiva Biotherapeutics Receives FDA Fast Track Designation for AlloNK® in Lupus Nephritis
Details : AlloNK (AB-101) is an allogeneic NK cell therapy designed to enhance antibody-dependent cellular cytotoxicity in combination with rituximab or obinutuzumab for treating lupus nephritis.
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 22, 2024
Lead Product(s) : AB-101,Cyclophosphamide,Rituximab
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AB-101,Rituximab
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AlloNK (AB-101) is a non-genetically modified, cord blood-derived, allogeneic, cryopreserved, ADCC-enhancing NK cell therapy candidate for use in combination with Combination with Rituximab in Lupus Nephritis.
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 16, 2023
Lead Product(s) : AB-101,Rituximab
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AB-201
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AB-201 is an allogeneic HER2-targeted CAR-NK cell therapy for the treatment of solid tumors in the outpatient setting with the option for repeat dosing. AB-201 has demonstrated potent anti-tumor activity in multiple preclinical HER2-positive tumor model ...
Product Name : AB-201
Product Type : Protein
Upfront Cash : Inapplicable
September 20, 2022
Lead Product(s) : AB-201
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AB-101,Interleukin 2,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AB-101, an ADCC enhancer NK-cell therapy candidate for use in combination with monoclonal antibodies or innate-cell engagers. Artiva is currently advancing a Phase 1/2 of AB-101 in combination with rituximab for the treatment of relapsed or refractory B-...
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 10, 2022
Lead Product(s) : AB-101,Interleukin 2,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AB-101,Interleukin 2,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Venrock Healthcare Capital Partners
Deal Size : $120.0 million
Deal Type : Series B Financing
Artiva Raises $120M in Series B Financing to Advance Pipeline of Allogeneic NK Cell Therapies
Details : Artiva’s pipeline includes AB-101, an ADCC enhancer NK-cell therapy which is currently under Phase 1/2 clinical trial in combination with rituximab for the treatment of relapsed or refractory B-cell lymphomas.
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 26, 2021
Lead Product(s) : AB-101,Interleukin 2,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Venrock Healthcare Capital Partners
Deal Size : $120.0 million
Deal Type : Series B Financing
Lead Product(s) : AB-MK-001
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Merck & Co
Deal Size : $1,866.0 million
Deal Type : Collaboration
Details : The collaboration initially includes two CAR-NK programs (AB-MK-001 and AB-MK-002) with an option for a third, none of which are in Artiva’s current or planned pipeline.
Product Name : AB-MK-001
Product Type : Cell and Gene therapy
Upfront Cash : $30.0 million
January 28, 2021
Lead Product(s) : AB-MK-001
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Merck & Co
Deal Size : $1,866.0 million
Deal Type : Collaboration
Lead Product(s) : AB-101,Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : 5Am Ventures
Deal Size : $78.0 million
Deal Type : Series A Financing
Artiva Biotherapeutics Launches with $78 Million Series A Financing to Advance NK Cell Therapies
Details : The company plans to enter the clinic this year with AB-101 in combination with an anti-CD20 monoclonal antibody for the treatment of relapsed refractory B-cell lymphoma.
Product Name : AlloNK
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 26, 2020
Lead Product(s) : AB-101,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : 5Am Ventures
Deal Size : $78.0 million
Deal Type : Series A Financing