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    [{"orgOrder":0,"company":"Artax Biopharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"AX-158","moa":"Nck-SH3.1 domain","graph1":"Dermatology","graph2":"Phase II","graph3":"Artax Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Artax Biopharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Artax Biopharma \/ Undisclosed"},{"orgOrder":0,"company":"Artax Biopharma","sponsor":"Simbec-Orion","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"AX-158","moa":"Nck-SH3.1 domain","graph1":"Immunology","graph2":"Phase I","graph3":"Artax Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals by Artax Biopharma

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                            01

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Achieves Clinical Validation of Oral Nck Modulator AX-158 for Autoimmune Disease

                            Details : AX-158 is a first-in-class, oral, Nck modulator, small molecule drug candidate, which is currently being evaluated for the treatment of mild to moderate plaque psoriasis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 22, 2025

                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $8.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Artax Biopharma Raises $8 Million Ahead of Phase 2a Data Expected in Q4-2024

                            Details : The financing aims to fund the Artax's lead asset, AX-158, is the first in a new class of Nck blockers, which is being evaluated in the mid-stage clinical trial studies for the treatment of psoriasis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            August 06, 2024

                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $8.0 million

                            Deal Type : Financing

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                            03

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Announces First Patient Dosed in Phase 2a Psoriasis Trial Evaluating AX-158

                            Details : AX-158 is a first in class oral Nck blocker, which is being evaluated in phase 2 clinical trials for the treatment of mild to moderate plaque psoriasis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 13, 2024

                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Artax Biopharma

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                            Global ChemShow
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                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Granted Clinical Trial Authorization for AX-158 Phase 2a Psoriasis Study

                            Details : AX-158 is a first-in-class, oral small molecule for the treatment of autoimmune diseases and selectively modulates, or adjusts, T Cell responses that play a critical role in immune system function. By selectively inhibiting Nck, a protein.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 09, 2023

                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Biopharma Announces Positive Phase 1 Results for AX-158, Company's First-in-Class Oral Immunomodulator D...

                            Details : AX-158 is a first-in-class, oral small molecule for the treatment of autoimmune diseases and selectively modulates, or adjusts, T Cell responses that play a critical role in immune system function. By selectively inhibiting Nck, a protein.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 01, 2023

                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Proof of Concept Study of AX-158 in Patients With Mild to Moderate Plaque Psoriasis

                            Details : AX-158 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Psoriasis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 13, 2023

                            Lead Product(s) : AX-158

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : $26.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Artax Biopharma Closes Financing to Advance Clinical Stage First-in-Class Oral Immunomodulator to Treat T Cell...

                            Details : Artax will use these funds to support the clinical development of AX-158 in autoimmune diseases, including the addition of key clinical development personnel. AX-158 has the potential to treat T Cell-mediated diseases without the risk of immunosuppressio...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 11, 2022

                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : $26.0 million

                            Deal Type : Financing

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                            08

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Simbec-Orion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral...

                            Details : AX-158 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Autoimmune Diseases.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 01, 2022

                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Simbec-Orion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Biopharma Granted MHRA Clinical Trial Authorization for AX-158

                            Details : In preclinical studies, AX-158 decreased key cytokines including INFγ, TNFα and IL-2. Based on this activity, Artax is planning future clinical development in autoimmune diseases, T cell malignancies and other related T cell pathologies.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 13, 2021

                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Artax Biopharma

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                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Artax Biopharma Announces Issuance of U.S. Composition of Matter Patent for Autoimmune Disease Program AX-158

                            Details : U.S. Patent covers AX-158, certain additional backup compounds, and pharmaceutical compositions thereof, and is expected to expire no earlier than 2039 in the United States.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 17, 2020

                            Lead Product(s) : AX-158

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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