
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...
Product Name : Salvecin
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 17, 2023
Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AR-301 (tosatoxumab), a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus, is being de...
Product Name : Salvecin
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 12, 2023
Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...
Product Name : Salvecin
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 20, 2023
Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...
Product Name : Salvecin
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 31, 2023
Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Suvratoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : AstraZeneca
Deal Size : $126.0 million
Deal Type : Termination
AstraZeneca Pulls Pneumonia Collab With Aridis Over Allegations Of A Missed Payment
Details : AstraZeneca terminated the collaboration with Aridis for the licensing of the AR-320 (suvratoxumab), a fully human, half-life extended IgG1 monoclonal antibody targeting S. aureus alpha toxin.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : $11.0 million
March 31, 2023
Lead Product(s) : Suvratoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : AstraZeneca
Deal Size : $126.0 million
Deal Type : Termination

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Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aridis Meets Primary and Secondary Endpoints in Phase 2a Study of AR-501 in Cystic Fibrosis Patients
Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 13, 2023
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AR-301 is a fully human IgG1 monoclonal antibody that targets S. aureus alpha-toxin (virulence factor that is secreted by both MRSA and MSSA). It is designed to protect against alpha-toxin mediated destruction of host cells, preserving a functional host ...
Product Name : Salvecin
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 25, 2023
Lead Product(s) : Tosatoxumab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
New Approaches to Treating Infections in Cystic Fibrosis Patients - AR 501 Phase 2 Trial Update
Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 17, 2023
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Cystic Fibrosis Foundation
Deal Size : $12.5 million
Deal Type : Funding
CF Foundation Invests Up to $4.85 Million in Aridis Pharmaceuticals for Testing of Anti-Infective
Details : AR-501 is a novel, small molecule and an inhalable form of gallium citrate, which acts as an iron analog to starve bacteria of iron. Gallium is believed to inhibit multiple iron-dependent synthetic and metabolic pathways required for pathogenicity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 12, 2022
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Cystic Fibrosis Foundation
Deal Size : $12.5 million
Deal Type : Funding

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Lead Product(s) : MBP134
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Recipient : Mapp Biopharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement
Details : The pan-Ebola program, MBP134, is a two mAb cocktail that has demonstrated effectiveness against Sudan virus (SUDV), Zaire Ebola virus (EBOV), Bundibugyo virus (BDBV), Taï Forest virus (TAFV), Reston virus (RESTV), and Bombali ebolavirus (BOMV).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
December 05, 2022
Lead Product(s) : MBP134
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Recipient : Mapp Biopharmaceutical
Deal Size : Undisclosed
Deal Type : Agreement
