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Disorders","country":"U.S.A","productType":"Peptide","year":"2020","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"Complement C3","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Apellis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Apellis Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Peptide","year":"2020","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"Complement C3","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved 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II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Apellis Pharmaceuticals \/ Apellis Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"Apellis Pharmaceuticals \/ Apellis Pharmaceuticals"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Affilogic","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FRANCE","productType":"Cell and Gene therapy","year":"2022","type":"Collaboration","leadProduct":"APL-1030","moa":"C3 receptor","graph1":"Neurology","graph2":"Preclinical","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Apellis Pharmaceuticals \/ Apellis Pharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Apellis Pharmaceuticals \/ Apellis Pharmaceuticals"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Peptide","year":"2021","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"Complement C3","graph1":"Nephrology","graph2":"Phase III","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Apellis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Apellis Pharmaceuticals \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Apellis Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Aspaveli (pegcetacoplan) is approved in the EU, other countries globally, and the US for the treatment of paroxysmal nocturnal haemoglobinuria (PNH) who have haemolytic anaemia, a rare blood disorder.

                          Product Name : Aspaveli

                          Product Type : Peptide

                          Upfront Cash : $275.0 million

                          July 01, 2025

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Approved FDF

                          Sponsor : Swedish Orphan Biovitrum AB

                          Deal Size : $300.0 million

                          Deal Type : Agreement

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                          02

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Aspaveli (pegcetacoplan) is the first and only approved therapy for geographic atrophy. Now it is being evaluated for the treatment of C3 glomerulopathy & IC-MPGN.

                          Product Name : Aspaveli

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          February 20, 2025

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Recipient : Swedish Orphan Biovitrum AB

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          January 27, 2025

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          October 06, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          September 20, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan injection) targets C3, being investigated for C3 glomerulopathy or primary immune complex membranoproliferative glomerulonephritis.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          August 08, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Swedish Orphan Biovitrum AB

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          June 28, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          April 26, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan injection) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          December 14, 2023

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          CPHI Shenzhen
                          Not Confirmed
                          CPHI Shenzhen
                          Not Confirmed

                          Details : Syfovre™ (pegcetacoplan injection) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          May 25, 2023

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Swedish Orphan Biovitrum AB

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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